Butyric Acid

A City of Hope study suggests a high-fiber diet may reduce graft-versus-host disease (GVHD) and myeloma risk in blood cancer patients post bone marrow/stem cell transplant, improving overall survival. High fiber intake was linked to reduced acute GVHD risk, better gut microbiome diversity, and higher butyrate levels, as shown in both human and mouse models.

New research explores gut microbiota's role in pancreatic cancer diagnosis and therapy, highlighting potential for early screening via microbial signatures and fecal microbiota transplantation (FMT) as a future treatment. Challenges in gut microbiome research are addressed, with machine learning and high-throughput sequencing technologies offering hope for early detection. Metabolomics suggests gut health influences systemic therapy efficacy, and FMT shows promise in animal studies for slowing tumor growth and improving survival, though human trials require rigorous donor screening.