Doconexent

Generic Name
Doconexent
Brand Names
Animi-3 With Vitamin D, Citranatal Harmony
Drug Type
Small Molecule
Chemical Formula
C22H32O2
CAS Number
6217-54-5
Unique Ingredient Identifier
ZAD9OKH9JC
Background

A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. It can be biosythesized from alpha-linolenic acid or commercially manufactured from microalgae. It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin, and retina thus plays an important role in their development and function. The amino-phospholipid DHA is found at a high concentration across several brain subcellular fractions, including nerve terminals, microsomes, synaptic vesicles, and synaptosomal plasma membranes .

Indication

Used as a high-docosahexaenoic acid (DHA) oral supplement.

Associated Conditions
Fredrickson classification type IV Hyperlipidemia, Fredrickson type IIb hyperlipidemia, Type III hyperlipidaemia
Associated Therapies
Nutritional supplementation

"Visiobiane Anti-age" Effects on Vision Parameters

Phase 4
Completed
Conditions
First Posted Date
2007-03-21
Last Posted Date
2011-10-06
Lead Sponsor
PiLeJe
Target Recruit Count
30
Registration Number
NCT00449917
Locations
🇫🇷

CRNH Clermont-Ferrand, Clermont-Ferrand, Auvergne, France

DHA Supplementation and Pregnancy Outcome

Phase 3
Completed
Conditions
Interventions
First Posted Date
2005-12-19
Last Posted Date
2016-03-14
Lead Sponsor
Susan Carlson, PhD
Target Recruit Count
350
Registration Number
NCT00266825
Locations
🇺🇸

Truman Medical Center, Kansas City, Missouri, United States

🇺🇸

University of Kansas Medical Center, Kansas City, Kansas, United States

Study of Docosahexaenoic Acid (DHA) Supplementation in Patients With X-Linked Retinitis Pigmentosa

Not Applicable
Completed
Conditions
First Posted Date
2000-02-25
Last Posted Date
2015-03-25
Lead Sponsor
Retina Foundation of the Southwest
Target Recruit Count
46
Registration Number
NCT00004827
© Copyright 2024. All Rights Reserved by MedPath