Alfimeprase

Generic Name
Alfimeprase
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
259074-76-5
Unique Ingredient Identifier
GPN9HBH1HS
Background

Alfimeprase is a recombinant analog of fibrolase. Fibrolase is a zinc-containing metalloproteinase isolated from the venom of the southern copperhead snake (Agkistrodon contortrix contortrix). It is a small protein that contains 203 residues (Randolph et al. 1992). Alfimeprase is being developed by Nuvelo.

Indication

Alfimeprase is being evaluated as a potential treatment for acute ischemic stroke, catheter occlusion (CO) and acute peripheral arterial occlusion (PAO).

Associated Conditions
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Associated Therapies
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