CDP323

Generic Name
CDP323
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
-
Unique Ingredient Identifier
9A54BAZ0YA
Background

CDP323 is an antagonist of the vascular cell adhesion molecule 1 (VCAM-1) binding to alpha4-integrins (other adhesion molecules), a process thought to be implicated in the pathophysiology of Multiple Sclerosis (MS). It is considered a small-molecule prodrug. CDP323 was originally developed by the British biopharmaceutical company Celltech plc. (now UCB S.A.) and is a putative new drug for oral treatment of multiple sclerosis.

Indication

Investigated for use/treatment in multiple sclerosis.

Associated Conditions
-
Associated Therapies
-

CDP323 Biomarker Study

Phase 1
Completed
Conditions
Interventions
First Posted Date
2008-08-01
Last Posted Date
2011-09-12
Lead Sponsor
UCB Pharma
Target Recruit Count
71
Registration Number
NCT00726648

Placebo Controlled Study in Subjects With Relapsing Forms of MS to Evaluate the Safety, Tolerability and Effects of CDP323

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2007-06-11
Last Posted Date
2011-09-12
Lead Sponsor
UCB Pharma
Target Recruit Count
232
Registration Number
NCT00484536
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