Bavituximab

Generic Name
Bavituximab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
648904-28-3
Unique Ingredient Identifier
Q16CT95N25
Background

Bavituximab is a chimeric Anti-PS monoclonal antibody analog which is used to potentially treat cancers and viral infections. It binds to phosphatidylserine and other exposed host cell lipids when induced by cellular stress. Additional analogs in the class include 3G4, 2aG4, 9d2 and Hu3g4.

Indication

Investigated for use/treatment in breast cancer, cancer/tumors (unspecified), HIV infection, hepatitis (viral, C), and solid tumors.

Associated Conditions
-
Associated Therapies
-

Safety and Efficacy Study of Bavituximab Plus Paclitaxel and Carboplatin to Treat Breast Cancer

Phase 2
Completed
Conditions
First Posted Date
2008-04-30
Last Posted Date
2011-03-24
Lead Sponsor
Peregrine Pharmaceuticals
Target Recruit Count
46
Registration Number
NCT00669565
Locations
๐Ÿ‡ฎ๐Ÿ‡ณ

Rajalakshmi Multispecialty Hospital, Bangalore, India

๐Ÿ‡ฎ๐Ÿ‡ณ

Apollo Specialty Hospitals, Chennai, India

๐Ÿ‡ฎ๐Ÿ‡ณ

Nizam's Institute of Medical Sciences, Hyderabaad, India

and more 6 locations

A Safety and Efficacy Study of Bavituximab Plus Docetaxel in Patients With Advanced Breast Cancer

Phase 2
Completed
Conditions
Interventions
First Posted Date
2008-04-30
Last Posted Date
2017-04-21
Lead Sponsor
Peregrine Pharmaceuticals
Target Recruit Count
46
Registration Number
NCT00669591
Locations
๐Ÿ‡ฌ๐Ÿ‡ช

Ltd. Oncological Center, Batumi, Georgia

๐Ÿ‡ฌ๐Ÿ‡ช

Ltd. Chemotherapy and Immunotherapy clinic Medulla 6, Jikia Str, Tbilisi, Georgia

๐Ÿ‡ฌ๐Ÿ‡ช

Ltd. Tbilisi Oncological Dispensary, Tblisi, Georgia

and more 1 locations

Bavituximab Repeat-Dose Trial in Patients Co-Infected With Chronic Hepatitis C Virus and Human Immunodeficiency Virus

Phase 1
Completed
Conditions
Interventions
First Posted Date
2007-07-18
Last Posted Date
2011-06-09
Lead Sponsor
Peregrine Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT00503347
Locations
๐Ÿ‡บ๐Ÿ‡ธ

AIDS Research Consortium of Atlanta, Atlanta, Georgia, United States

๐Ÿ‡บ๐Ÿ‡ธ

Johns Hopkins University, Center for Viral Hepatitis, Baltimore, Maryland, United States

๐Ÿ‡บ๐Ÿ‡ธ

Saint Michael's Medical Center, Newark, New Jersey, United States

and more 3 locations

Repeat-Dose Study of Bavituximab in Patients With Chronic Hepatitis C

Phase 1
Completed
Conditions
First Posted Date
2006-06-23
Last Posted Date
2008-05-07
Lead Sponsor
Peregrine Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT00343525
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University Hepatitis Center at Bach & Godofsky MD PA, Sarasota, Florida, United States

๐Ÿ‡บ๐Ÿ‡ธ

Alamo Medical Research, San Antonio, Texas, United States

Study of Bavituximab in Patients With Advanced Solid Tumor Malignancies

Phase 1
Completed
Conditions
Interventions
First Posted Date
2005-08-11
Last Posted Date
2011-03-01
Lead Sponsor
Peregrine Pharmaceuticals
Target Recruit Count
28
Registration Number
NCT00129337
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Arizona Cancer Center, Tucson, Arizona, United States

๐Ÿ‡บ๐Ÿ‡ธ

The West Clinic, Memphis, Tennessee, United States

๐Ÿ‡บ๐Ÿ‡ธ

Premiere Oncology, Santa Monica, California, United States

and more 3 locations

Study of Bavituximab in Patients With Chronic Hepatitis C Virus Infection

Phase 1
Completed
Conditions
First Posted Date
2005-08-09
Last Posted Date
2008-05-07
Lead Sponsor
Peregrine Pharmaceuticals
Target Recruit Count
32
Registration Number
NCT00128271
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Bach & Godofsky, MD, PA, Bradenton, Florida, United States

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