CG0070
- Generic Name
- CG0070
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- -
- CAS Number
- -
- Unique Ingredient Identifier
- -
- Background
CG0070 is investigated in clinical trials for treating bladder cancer. CG0070 is a solid. CG0070 can potentially destroy cancer cells by two different mechanisms: direct cell killing by the virus and immune-mediated cell killing stimulated by GM-CSF. CG0070, an oncolytic virus therapy with specificity for multiple cancers, has been evaluated in numerous preclinical studies. It has been engineered to secrete GM-CSF, an immune stimulating hormone, which also serves as the adjuvant in cancer immunotherapy.
- Indication
Investigated for use/treatment in bladder cancer.
- Associated Conditions
- -
- Associated Therapies
- -
Study of CG0070 After Transurethral Resection in Patients With IR NMIBC
- First Posted Date
- 2024-02-12
- Last Posted Date
- 2024-12-24
- Target Recruit Count
- 20
- Registration Number
- NCT06253845
- Locations
- 🇺🇸
Moffitt Cancer Center, Tampa, Florida, United States
Study of CG0070 Combined With Nivolumab in Cisplatin Ineligible Patients With MIBC
- Conditions
- Interventions
- First Posted Date
- 2020-10-30
- Last Posted Date
- 2024-12-13
- Target Recruit Count
- 21
- Registration Number
- NCT04610671
- Locations
- 🇺🇸
Moffitt Cancer Center, Tampa, Florida, United States
Study of CG0070 Given in Combination With Pembrolizumab, in Non-Muscle Invasive Bladder Cancer, Unresponsive to Bacillus Calmette-Guerin
- Conditions
- Interventions
- First Posted Date
- 2020-05-13
- Last Posted Date
- 2022-08-24
- Lead Sponsor
- CG Oncology, Inc.
- Target Recruit Count
- 35
- Registration Number
- NCT04387461
- Locations
- 🇺🇸
Moffitt Cancer Center, Tampa, Florida, United States
🇺🇸Northwestern University, Tampa, Florida, United States
🇺🇸Johns Hopkins Medical Institution, Baltimore, Maryland, United States
Drug Development Updates
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