Interferon alfa

Generic Name
Interferon alfa
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
-
Unique Ingredient Identifier
-
Background

Natural interferon alpha or Multiferon is obtained from the leukocyte fraction of human blood following induction with Sendai virus. Interferon alfa contains several naturally occurring IFN-α subtypes and is purified by affinity chromatography. Interferon alpha proteins are mainly involved in innate immune response against viral infection. They come in 13 su...

Indication

Investigated for use/treatment in hepatitis (viral, C), leukemia (lymphoid), leukemia (myeloid), leukemia (unspecified), and melanoma.

Associated Conditions
Follicular Non-Hodgkin's Lymphoma, Hematological Malignancy, Hepatitis C Virus (HCV) Infection, Malignant Melanoma, Renal Cell Carcinoma (RCC), Viral Hepatitis B
Associated Therapies
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Interferon-α for TP53 Myeloid Malignancy Post Allo-HSCT

Phase 2
Recruiting
Conditions
Interventions
First Posted Date
2023-11-14
Last Posted Date
2024-03-21
Lead Sponsor
Peking University People's Hospital
Target Recruit Count
35
Registration Number
NCT06130579
Locations
🇨🇳

Deparment of Hematology, Peking University People's Hospital, Beijing, Beijing, China

COVID-19 Prevention and Treatment in Cancer; a Sequential Multiple Assignment Randomised Trial;

First Posted Date
2020-09-01
Last Posted Date
2023-08-24
Lead Sponsor
Peter MacCallum Cancer Centre, Australia
Target Recruit Count
441
Registration Number
NCT04534725
Locations
🇦🇺

St Vincent's Hospital, Fitzroy, Victoria, Australia

🇦🇺

Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia

🇦🇺

Royal Melbourne Hospital, Melbourne, Victoria, Australia

and more 2 locations

Cytokines in Patients With Metastatic Renal Cell Carcinoma of Intermediate Prognosis

Phase 3
Completed
Conditions
First Posted Date
2006-02-14
Last Posted Date
2006-02-16
Lead Sponsor
Centre Leon Berard
Target Recruit Count
456
Registration Number
NCT00291369
Locations
🇫🇷

Centre Leon Berard, Lyon, France

Study Evaluating Interferon And CCI-779 In Advanced Renal Cell Carcinoma

First Posted Date
2003-07-25
Last Posted Date
2012-10-25
Lead Sponsor
Pfizer
Target Recruit Count
626
Registration Number
NCT00065468
Locations

Pfizer Investigational Site

Phase III Randomized Study of High Vs Standard Dose of Interferon Alfa for Chronic Hepatitis C

Phase 3
Completed
Conditions
First Posted Date
2000-02-25
Last Posted Date
2005-06-24
Lead Sponsor
National Center for Research Resources (NCRR)
Target Recruit Count
57
Registration Number
NCT00004804
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