ICA-105665

Generic Name: ICA-105665

Brand Names: -

Drug Type: Small Molecule

Chemical Formula: -

CAS Number: -

Unique Ingredient Identifier: -

Background: ICA-105665 is a novel small molecule compound for the treatment of epilepsy. It is a novel opener of the KCNQ ion channel which in preclinical studies has demonstrated a broad spectrum of activity in models of epilepsy. In addition, ICA-105665 has also demonstrated activity in certain models of neuropathic pain.

Indication: Investigated for use/treatment in epilepsy.

Associated Conditions: -

Associated Therapies: -

Clinical Trials

A Study to Investigate the Effect of ICA-105665 in Photosensitive Epilepsy Patients

Phase 2

Terminated

Conditions: Epilepsy

Interventions: Drug: ICA-105665

First Posted Date: 2009-09-17

Last Posted Date: 2012-10-04

Lead Sponsor: Pfizer

Target Recruit Count: 13

Registration Number: NCT00979004

Locations: 🇺🇸
Pfizer Investigational Site, Nashville, Tennessee, United States

Effects of ICA-105665 Using the Intradermal Capsaicin and Ultraviolet B (UV-B) Models in Healthy Male Subjects

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: ICA-105665
Drug: Placebo
Drug: Ibuprofen

First Posted Date: 2009-08-20

Last Posted Date: 2012-09-28

Lead Sponsor: Pfizer

Target Recruit Count: 25

Registration Number: NCT00962663

Locations: Pfizer Investigational Site

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