Ridaforolimus

Generic Name
Ridaforolimus
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C53H84NO14P
CAS Number
572924-54-0
Unique Ingredient Identifier
48Z35KB15K
Indication

Investigated for use/treatment in solid tumors, sarcoma, cancer/tumors (unspecified), endometrial cancer, prostate cancer, and bone metastases.

Associated Conditions
-
Associated Therapies
-

Study of Ridaforolimus (MK-8669) in Participants With Solid Tumors (MK-8669-003)(COMPLETED)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2008-06-10
Last Posted Date
2024-05-21
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
13
Registration Number
NCT00694083

Safety, Tolerability and Maximum Tolerated Dose of Oral AP23573 in Combination With Doxorubicin (8669-015)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2006-02-08
Last Posted Date
2015-07-22
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
37
Registration Number
NCT00288431

AP23573 in Female Adult Patients With Recurrent or Persistent Endometrial Cancer (8669-019)(COMPLETED)

Phase 2
Completed
Conditions
Interventions
First Posted Date
2005-07-22
Last Posted Date
2015-02-19
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
45
Registration Number
NCT00122343

Study of Oral Ridaforolimus (AP23573, MK-8669) to Treat Patients With Refractory or Advanced Malignancies (MK-8669-016 AM4)(COMPLETED)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2005-06-03
Last Posted Date
2015-02-12
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
147
Registration Number
NCT00112372

Ridaforolimus (AP23573/MK-8669) in Participants With Taxane-Resistant Androgen-Independent Prostate Cancer (AIPC)(MK-8669-017)

Phase 2
Completed
Conditions
Interventions
First Posted Date
2005-05-05
Last Posted Date
2015-11-20
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
39
Registration Number
NCT00110188
Locations
🇺🇸

Louis Warchaw Prostate Cancer Center, Cedars-Sinai Medical Center, Los Angeles, California, United States

🇺🇸

University of Wisconsin, Madison, WI, Madison, Wisconsin, United States

🇺🇸

Beth Israel Deaconess Medical Center/MGH/DFCI, Boston, Massachusetts, United States

and more 1 locations

Study of AP23573 in Patients With Relapsed or Refractory Hematologic Malignancies (8669-024)(COMPLETED)

First Posted Date
2004-06-28
Last Posted Date
2015-08-19
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
57
Registration Number
NCT00086125
Locations
🇺🇸

University of Chicago Hospitals, Section of Hematology/Oncology, Chicago, Illinois, United States

🇺🇸

The Cancer Institute of New Jersey, New Brunswick, New Jersey, United States

🇺🇸

MD Anderson Cancer Center, Houston, Texas, United States

and more 5 locations

Safety Study of Ridaforolimus in Patients With Advanced, Refractory or Recurrent Malignancies (MK-8669-001 AM5)(COMPLETED)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2003-05-12
Last Posted Date
2015-08-27
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
46
Registration Number
NCT00060632

Safety Study of AP23573 in Patients With Advanced, Refractory or Recurrent Malignancies (8669-013)(COMPLETED)

Phase 1
Completed
Conditions
Interventions
First Posted Date
2003-05-12
Last Posted Date
2015-08-27
Lead Sponsor
Merck Sharp & Dohme LLC
Target Recruit Count
33
Registration Number
NCT00060645
Locations
🇺🇸

Cancer Therapy and Research Center, University of Texas Health Center at San Antonio, San Antonio, Texas, United States

© Copyright 2024. All Rights Reserved by MedPath