Sitaxentan

Generic Name
Sitaxentan
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C18H15ClN2O6S2
CAS Number
184036-34-8
Unique Ingredient Identifier
J9QH779MEM
Background

Sitaxentan was marketed under the trade name Thelin for the treatment of pulmonary arterial hypertension (PAH) by Encysive Pharmaceuticals until Pfizer purchased Encysive in February 2008. In 2010, Pfizer voluntarily removed sitaxentan from the market over concerns of hepatotoxicity.

Indication

Investigated for use/treatment in pulmonary hypertension, connective tissue diseases, hypertension, and congestive heart failure.

Associated Conditions
-
Associated Therapies
-
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