Asparaginase Erwinia chrysanthemi
- Generic Name
- Asparaginase Erwinia chrysanthemi
- Brand Names
- Erwinaze, Rylaze, Enrylaze
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 1349719-22-7
- Unique Ingredient Identifier
- D733ET3F9O
- Background
Asparaginase Erwinia chrysanthemi is an asparaginase-specific enzyme derived from Erwinia chrysanthemi used as an anticancer agent. It works by depleting the stores of an important amino acid called asparagine, which is involved in DNA synthesis and cell survival of malignant cells, leading to cell death. L-asparaginase was first identified in 1963, and ther...
- Indication
Asparaginase Erwinia chrysanthemi is indicated as a component of a multi-agent chemotherapeutic regimen for the treatment of patients with acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma in adults and children who have developed hypersensitivity to E. coli-derived asparaginase.
- Associated Conditions
- Acute Lymphoblastic Leukaemias (ALL), Lymphoblastic Lymphoma
- Associated Therapies
- -
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