Overview
Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially as a fire retardant. It can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers).
Background
Magnesium hydroxide is an inorganic compound. It is naturally found as the mineral brucite. Magnesium hydroxide can be used as an antacid or a laxative in either an oral liquid suspension or chewable tablet form. Additionally, magnesium hydroxide has smoke suppressing and flame retardant properties and is thus used commercially as a fire retardant. It can also be used topically as a deodorant or for the relief of canker sores (aphthous ulcers).
Indication
Magnesium hydroxide can be used as an antacid or a laxative depending on the administered dose. As an antacid, it is used for the temporary relief of heartburn, upset stomach, sour stomach or acid indigestion. As a laxative, it is used for the relief of occasional constipation by promoting bowel movements for 30 minutes and up to 6 hours.
Associated Conditions
- Colic
- Constipation
- Dyspepsia
- Flatulence
- Gastric Ulcer
- Heartburn
- Upset stomach
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2021/06/18 | N/A | Withdrawn | |||
2021/03/17 | Phase 2 | UNKNOWN | Dinara Zhumanbayeva | ||
2020/02/13 | Phase 1 | Completed |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| Geri-Care Pharmaceuticals, Corp | 57896-001 | ORAL | 1200 mg in 15 mL | 3/31/2025 | |
| Cardinal Health 107, LLC | 55154-9429 | ORAL | 200 mg in 5 mL | 5/1/2025 | |
| Geri-Care Pharmaceuticals, Corp | 57896-004 | ORAL | 200 mg in 5 mL | 3/31/2025 | |
| ATLANTIC BIOLOGICALS CORP. | 17856-0630 | ORAL | 200 mg in 5 mL | 5/12/2025 | |
| Geri-Care Pharmaceuticals, Corp | 57896-002 | ORAL | 1200 mg in 15 mL | 3/31/2025 | |
| ATLANTIC BIOLOGICALS CORP. | 17856-5725 | ORAL | 400 mg in 5 mL | 5/23/2025 | |
| Contract Pharmacal Corp. | 10267-0041 | ORAL | 200 mg in 1 1 | 6/16/2025 | |
| Contract Pharmacal Corp. | 10267-0020 | ORAL | 135 mg in 1 1 | 5/23/2025 | |
| ATLANTIC BIOLOGICALS CORP. | 17856-0788 | ORAL | 1200 mg in 15 mL | 5/23/2025 | |
| Chattem, Inc. | 41167-0257 | ORAL | 600 mg in 1 1 | 3/31/2025 |
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| AXCEL EVILINE FORTE SUSPENSION | SIN06400P | SUSPENSION | 400 mg/5 ml | 7/4/1991 | |
| HYDROSIL TABLET | SIN03484P | TABLET | 200 mg | 6/24/1989 | |
| MACGEL TABLET | SIN08119P | TABLET | 200 mg | 4/11/1995 | |
| ACTAL PLUS TABLET | SIN07376P | TABLET | 152 mg | 3/29/1993 | |
| GASTROGEL ANTACID | SIN02976P | SUSPENSION | 24 mg/ml | 5/26/1989 | |
| AXCEL EVILINE TABLET | SIN06592P | TABLET | 200 mg | 9/26/1991 |
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| VIDA-MECO SUSP ORAL | N/A | N/A | N/A | 2/6/1987 | |
| SIMWELL CHEWABLE TABLETS | N/A | N/A | N/A | 11/6/2017 | |
| GASEDIN-U EXTRA STOMACH CHEWABLE TAB | N/A | N/A | N/A | 12/28/2006 | |
| MAALOX PLUS TAB | N/A | N/A | N/A | 10/12/1978 | |
| FEDRA-GEL-S CHEWABLE TAB | N/A | N/A | N/A | 7/4/1984 | |
| WEICHI TAB | N/A | N/A | N/A | 5/3/1995 |
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| MYLANTA 2go ANTACID ORIGINAL chewable tablet (reformulation) blister pack | 118511 | Medicine | A | 5/11/2005 | |
| GASTROGEL ANTACID oral liquid bottle | 13452 | Medicine | A | 8/30/1991 | |
| MYLANTA DOUBLE STRENGTH oral liquid bottle (reformulation 2) | 126090 | Medicine | A | 3/10/2006 | |
| MYLANTA ANTACID DOUBLE STRENGTH oral liquid bottle | 294406 | Medicine | A | 9/27/2017 | |
| MYLANTA P ANTACID oral liquid bottle (reformulation) | 121994 | Medicine | A | 9/19/2005 | |
| MYLANTA ORIGINAL oral liquid bottle (reformulation 2) | 122007 | Medicine | A | 9/19/2005 | |
| MYLANTA ANTACID ORIGINAL oral liquid bottle | 294405 | Medicine | A | 9/27/2017 | |
| Magnesia San Pellegrino Lemon Effervescent Powder | 10156 | Medicine | A | 6/24/1991 | |
| MYLANTA P ANTACID chewable tablet blister pack | 118509 | Medicine | A | 5/11/2005 | |
| MYLANTA 2go ANTACID DOUBLE STRENGTH chewable tablet (reformulation) blister pack | 118508 | Medicine | A | 5/11/2005 |