Tegafur-uracil
- Generic Name
- Tegafur-uracil
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C12H13FN4O5
- CAS Number
- 74578-38-4
- Unique Ingredient Identifier
- HMI5GR78FR
- Background
Tegafur-uracil is an anti-tumor compound containing tegafur (1-(2-tetrahydrofuryl)-5-fluorouracil) and uracil in a molar ratio of 1:4. It was developed as an anti-cancer therapy by Taiho Pharmaceutical Co Ltd. It is approved in different countries but it is not yet approved by the FDA, Health Canada or EMA.
- Indication
Tegafur-uracil is indicated for the first line treatment of metastatic colorectal cancer with concomitant administration of calcium folinate. Colorectal cancer is the third most diagnosed cancer and 30% of the cases can present the metastatic state.
- Associated Conditions
- -
- Associated Therapies
- -
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