Povidone

Generic Name
Povidone
Brand Names
Clear Eyes Natural Tears, Colirio Ocusan, Minidrops, Refresh Lubricant, Stye
Drug Type
Small Molecule
Chemical Formula
-
CAS Number
9003-39-8
Unique Ingredient Identifier
FZ989GH94E
Background

Povidone, also known as polyvinylpyrrolidone (PVP) or polyvidone, is a synthetic water-soluble polymer made from the monomer N-vinylpyrrolidone used as a binder in many pharmaceutical tablets and lubricant in eye drops. It is also used in many technical applications with various roles as an adhesive, additive, and emulsifier. When in complex with iodine, Povidone-iodine displays antiseptic properties where the iodine, a bactericidal component, mainly contributes to this effect, and povidone acts as a carrier . Povidone-iodine can be found in over-the-counter topical solutions, ointment, pessaries, liquid soaps and surgical scrubs. The clinical effectiveness of Povidone-iodine on wound healing remains somewhat controversial, as it was demonstrated in a few clinical studies that the application of the compound in wounds was associated with impaired wound healing, reduced wound strength, or infection in open wounds .

The FDA withdrew its approval for the use of all intravenous drug products containing povidone. Other formulations of povidone continue to be available.

Indication

When in complex with iodine, indicated for inducing antisepsis for prevention of infection in minor cuts, scrapes, and burns.

Associated Conditions
Dry Eyes
Associated Therapies
Skin disinfection
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