Vinflunine
- Generic Name
- Vinflunine
- Brand Names
- Javlor
- Drug Type
- Small Molecule
- Chemical Formula
- C45H54F2N4O8
- CAS Number
- 162652-95-1
- Unique Ingredient Identifier
- 5BF646324K
- Background
Vinflunine is a third-generation member of the vinca alkaloid family with anti-tumour actions. It was first described in 1998 at the Pierre Fabre research center in France. Like other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death via apoptosis . Vinflunine is a microtubule inhibit...
- Indication
For use as a monotherapy in adults with advanced or transitional cell carcinoma of the urothelial tract after failure of a prior platinum-containing therapy .
- Associated Conditions
- Transitional Cell Carcinoma of the Urothelial Tract, Metastatic Transitional Cell Carcinoma of the Urothelial Tract
- Associated Therapies
- -
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