Naldemedine
- Generic Name
- Naldemedine
- Brand Names
- Symproic, Rizmoic
- Drug Type
- Small Molecule
- Chemical Formula
- C32H34N4O6
- CAS Number
- 916072-89-4
- Unique Ingredient Identifier
- 03KSI6WLXH
- Background
Naldemedine is an opioid receptor antagonist . It is a modified form of Naltrexone to which a side chain has been added to increase molecular weight and polar surface area resulting in restricted transport across the blood brain barrier. Naldemedine was approved in 2017 in both the US and Japan for the treatment of Opioid-induced Constipation.
- Indication
For the treatment of opioid-induced constipation .
- Associated Conditions
- Opioid Induced Constipation (OIC)
- Associated Therapies
- -
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