PF-00489791
- Generic Name
- PF-00489791
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C20H28N8O4S
- CAS Number
- 853003-48-2
- Unique Ingredient Identifier
- 2S27T3DSZ3
- Background
PF-00489791 has been used in trials studying the treatment of Hypertension, Raynaud's Disease, Diabetic Nephropathies, Hypertension, Pulmonary, and Peripheral Vascular Disease.
- Associated Conditions
- -
- Associated Therapies
- -
A Study to Estimate the Effect of CYP3A4 Inhibitors (Itraconazole, Diltiazem or Verapamil) on the Pharmacokinetics of Single Dose PF- 00489791 in Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2014-12-18
- Last Posted Date
- 2016-09-16
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 22
- Registration Number
- NCT02319148
- Locations
- ๐ง๐ช
Pfizer Clinical Research Unit, Brussels, Belgium
A Phase 2, Placebo-Controlled Study To Evaluate The Efficacy And Safety Of PF-00489791 In Patients With Type 2 Diabetes And Overt Nephropathy
- First Posted Date
- 2010-09-13
- Last Posted Date
- 2019-03-12
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 256
- Registration Number
- NCT01200394
- Locations
- ๐บ๐ธ
North America Research Institute, Azusa, California, United States
๐บ๐ธCalifornia Kidney Specialists, San Dimas, California, United States
๐บ๐ธResearch Across America, Houston, Texas, United States
PF-00489791 For The Treatment Of Raynaud's
- Conditions
- Interventions
- First Posted Date
- 2010-03-22
- Last Posted Date
- 2018-05-16
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 243
- Registration Number
- NCT01090492
- Locations
- ๐บ๐ธ
Stanford Hospital and Outpatient Center, Redwood City, California, United States
๐บ๐ธDiagnostic Rheumatology and Research, PC, Indianapolis, Indiana, United States
๐บ๐ธArthritis and Rheumatology of Georgia, Atlanta, Georgia, United States
A Research Study To Assess The Effectiveness And Safety Of Different Doses Of Oral PF-00489791 In The Treatment Of Adult Patients With Pulmonary Arterial Hypertension
- Conditions
- Interventions
- First Posted Date
- 2009-03-02
- Last Posted Date
- 2017-10-24
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 48
- Registration Number
- NCT00853112
- Locations
- ๐ฉ๐ช
Thoraxklinik am Universitaetsklinikum, Heidelberg, Germany
๐ฎ๐ณDepartment Of Cardiology, Sri Venkateswara Institute Of Medical Sciences, Tirupati, Andhra Pardesh, India
๐จ๐ฆLawson Health Research Institute, London, Ontario, Canada
A Dose Finding Study Of PF-00489791 In Patients With Mild To Moderate High Blood Pressure
- First Posted Date
- 2007-01-17
- Last Posted Date
- 2021-10-11
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 135
- Registration Number
- NCT00422461
- Locations
- ๐บ๐ธ
Orange County Research Center, Tustin, California, United States
๐บ๐ธRiser Medical Associates, Picayune, Mississippi, United States
๐บ๐ธPiedmont Medical Research Associates, Winston-Salem, North Carolina, United States
Drug Development Updates
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