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Valspodar

Generic Name
Valspodar
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C63H111N11O12
CAS Number
121584-18-7
Unique Ingredient Identifier
Q7ZP55KF3X
Background

Valspodar has been used in trials studying the treatment of Cancer, Sarcoma, Leukemia, Lymphoma, and Breast Cancer, among others.

Associated Conditions
-
Associated Therapies
-

Combination Chemotherapy Plus PSC-833 in Treating Children With Refractory or Relapsed Acute Leukemia

Phase 1
Completed
Conditions
Leukemia
Interventions
First Posted Date
2004-04-29
Last Posted Date
2013-02-01
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
3
Registration Number
NCT00002912
Locations
🇺🇸

Cancer Institute of New Jersey, New Brunswick, New Jersey, United States

🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

🇺🇸

Simmons Cancer Center - Dallas, Dallas, Texas, United States

and more 52 locations

Combination Chemotherapy With or Without Valspodar in Treating Patients With Previously Untreated Acute Myeloid Leukemia

Phase 3
Completed
Conditions
Adult Acute Megakaryoblastic Leukemia (M7)
Adult Acute Minimally Differentiated Myeloid Leukemia (M0)
Adult Acute Monoblastic Leukemia (M5a)
Adult Acute Monocytic Leukemia (M5b)
Adult Acute Myeloblastic Leukemia With Maturation (M2)
Adult Acute Myeloblastic Leukemia Without Maturation (M1)
Adult Acute Myeloid Leukemia With 11q23 (MLL) Abnormalities
Adult Acute Myeloid Leukemia With Del(5q)
Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)
Adult Acute Myeloid Leukemia With t(16;16)(p13;q22)
Interventions
First Posted Date
2003-10-28
Last Posted Date
2013-06-04
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
640
Registration Number
NCT00003190
Locations
🇺🇸

Cancer and Leukemia Group B, Chicago, Illinois, United States

Combination Chemotherapy With or Without PSC 833, Peripheral Stem Cell Transplantation, and/or Interleukin-2 in Treating Patients With Acute Myeloid Leukemia

Phase 3
Completed
Conditions
Adult Acute Eosinophilic Leukemia
Adult Acute Erythroid Leukemia (M6)
Adult Acute Megakaryoblastic Leukemia (M7)
Adult Acute Basophilic Leukemia
Adult Acute Minimally Differentiated Myeloid Leukemia (M0)
Adult Acute Monoblastic Leukemia (M5a)
Adult Acute Monoblastic Leukemia and Acute Monocytic Leukemia (M5)
Adult Acute Monocytic Leukemia (M5b)
Adult Acute Myeloblastic Leukemia With Maturation (M2)
Adult Acute Myeloblastic Leukemia Without Maturation (M1)
Interventions
Drug: cytarabine
Biological: aldesleukin
Other: clinical observation
Drug: daunorubicin hydrochloride
Biological: filgrastim
Drug: etoposide
Other: pharmacological study
Drug: valspodar
Drug: busulfan
Procedure: autologous hematopoietic stem cell transplantation
Procedure: peripheral blood stem cell transplantation
First Posted Date
2003-01-27
Last Posted Date
2013-06-04
Lead Sponsor
National Cancer Institute (NCI)
Target Recruit Count
720
Registration Number
NCT00006363
Locations
🇺🇸

Cancer and Leukemia Group B, Chicago, Illinois, United States

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