Urelumab

Generic Name
Urelumab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
934823-49-1
Unique Ingredient Identifier
230902QLLC
Background

Urelumab has been used in trials studying the treatment of Leukemia, Multiple Myeloma, Malignant Tumors, and Cancer - Solid Tumors and B-Cell Non-Hodgkin's Lymphoma. Urelumab is a fully human antibody that targets CD137. The antibody product was developed using Medarex's UltiMAb(R) technology and was the first UltiMAb- derived antibody in clinical developmen...

Associated Conditions
-
Associated Therapies
-

Stereotactic Body Radiotherapy (SBRT) Plus Immunotherapy for Cancer

First Posted Date
2018-02-13
Last Posted Date
2023-02-16
Lead Sponsor
University of Chicago
Target Recruit Count
60
Registration Number
NCT03431948
Locations
🇺🇸

University of Chicago Medical Center, Chicago, Illinois, United States

Study of Urelumab in Subjects With Advanced and/or Metastatic Malignant Tumors

Phase 1
Completed
Conditions
Interventions
First Posted Date
2015-08-27
Last Posted Date
2020-05-18
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
18
Registration Number
NCT02534506
Locations
🇯🇵

Local Institution, Kobe-shi, Hyogo, Japan

Platform Study of Neoadjuvant and Adjuvant Immunotherapy for Patients With Resectable Adenocarcinoma of the Pancreas

First Posted Date
2015-05-22
Last Posted Date
2024-12-06
Lead Sponsor
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Target Recruit Count
76
Registration Number
NCT02451982
Locations
🇺🇸

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States

Urelumab (CD137 mAb) With Rituximab for Relapsed, Refractory or High-risk Untreated Chronic Lymphocytic Leukemia (CLL) Patients

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2015-04-20
Last Posted Date
2016-12-06
Lead Sponsor
M.D. Anderson Cancer Center
Registration Number
NCT02420938

A Phase I Open Label Study of the Safety and Tolerability of Elotuzumab (BMS-901608) Administered in Combination With Either Lirilumab (BMS-986015) or Urelumab (BMS-663513) in Subjects With Multiple Myeloma

First Posted Date
2014-09-30
Last Posted Date
2017-11-01
Lead Sponsor
Bristol-Myers Squibb
Target Recruit Count
44
Registration Number
NCT02252263
Locations
🇪🇸

Local Institution, Pamplona, Navarra, Spain

🇺🇸

The Ohio State University, Columbus, Ohio, United States

🇺🇸

Memorial Sloan Kettering Cancer Center, New York, New York, United States

and more 4 locations
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