Demcizumab

Generic Name
Demcizumab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
1243262-17-0
Unique Ingredient Identifier
SF168W7FW0
Background

Demcizumab is under investigation for the treatment of Nonsquamous Nonsmall Cell Neoplasm of Lung.

Associated Conditions
-
Associated Therapies
-

A Phase 1b Study of Demcizumab Plus Pembrolizumab in Locally Advanced or Metastatic Solid Tumors

First Posted Date
2016-03-30
Last Posted Date
2020-08-11
Lead Sponsor
OncoMed Pharmaceuticals, Inc.
Target Recruit Count
29
Registration Number
NCT02722954
Locations
🇬🇧

The Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom

🇺🇸

The START Center for Cancer Care, San Antonio, Texas, United States

🇺🇸

Rocky Mountain Cancer Center, Denver, Colorado, United States

and more 3 locations

Study of Gemcitabine, Abraxane® Plus Placebo Versus Gemcitabine, Abraxane® Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With 1st-Line Metastatic Pancreatic Ductal Adenocarcinoma

First Posted Date
2014-11-13
Last Posted Date
2020-09-28
Lead Sponsor
OncoMed Pharmaceuticals, Inc.
Target Recruit Count
207
Registration Number
NCT02289898
Locations
🇺🇸

Lynn Cancer Institute, Boca Raton, Florida, United States

🇺🇸

University of Kansas Cancer Center, Westwood, Kansas, United States

🇦🇺

St John of God Murdoch Hospital, Murdoch, Western Australia, Australia

and more 38 locations

A Study of Carboplatin, Pemetrexed Plus Placebo vs Carboplatin, Pemetrexed Plus 1 or 2 Truncated Courses of Demcizumab in Subjects With Non-Squamous Non-Small Cell Lung Cancer

First Posted Date
2014-10-08
Last Posted Date
2020-09-09
Lead Sponsor
OncoMed Pharmaceuticals, Inc.
Target Recruit Count
82
Registration Number
NCT02259582
Locations
🇧🇪

Centre Hospitalier Jolimont-Lobbes, La Louviere, Belgium

🇺🇸

Roswell Park Cancer Institute, Buffalo, New York, United States

🇺🇸

Gabrail Cancer Center Research, Canton, Ohio, United States

and more 40 locations

A Study of Demcizumab Plus Paclitaxel in Subjects With Platinum Resistant Ovarian

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2013-09-27
Last Posted Date
2020-09-09
Lead Sponsor
OncoMed Pharmaceuticals, Inc.
Target Recruit Count
20
Registration Number
NCT01952249
Locations
🇺🇸

University of Oklahoma Stephenson Cancer Center, Oklahoma City, Oklahoma, United States

🇺🇸

The University of Texas MD Anderson Cancer Center Department of Gynecologic Oncology, Houston, Texas, United States

🇺🇸

University of Pennsylvania, Philadelphia, Pennsylvania, United States

A Study of Carboplatin and Pemetrexed Plus Demcizumab (OMP-21M18) in Subjects With Non-Squamous Non-Small Cell Lung Cancer

Phase 1
Completed
Conditions
Interventions
First Posted Date
2010-08-27
Last Posted Date
2020-09-09
Lead Sponsor
OncoMed Pharmaceuticals, Inc.
Target Recruit Count
50
Registration Number
NCT01189968
Locations
🇪🇸

START Madrid, Madrid, Spain

🇦🇺

Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia

🇦🇺

Monash Medical Centre, Clayton, Victoria, Australia

and more 4 locations

A Study of Gemcitabine and Demcizumab (OMP-21M18) With or Without Abraxane® as 1st-line Treatment in Subjects With Locally Advanced or Metastatic Pancreatic Cancer

First Posted Date
2010-08-27
Last Posted Date
2020-09-09
Lead Sponsor
OncoMed Pharmaceuticals, Inc.
Target Recruit Count
57
Registration Number
NCT01189929
Locations
🇪🇸

START Madrid, Madrid, Spain

🇦🇺

Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia

🇳🇿

Christchurch Hospital, Christchurch, New Zealand

and more 3 locations
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