Clazakizumab

Generic Name
Clazakizumab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
1236278-28-6
Unique Ingredient Identifier
4S38Z8RA9O
Background

Clazakizumab has been used in trials studying the treatment of Rheumatoid Arthritis.

Associated Conditions
-
Associated Therapies
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news-medical.net
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Phase 3 trial assesses clazakizumab in kidney transplant recipients with caAMR

Clazakizumab failed to meet primary efficacy outcomes in the IMAGINE Phase 3 trial for chronic active antibody-mediated rejection (caAMR) in kidney transplant recipients, showing no difference in eGFR change from baseline at week 52 compared to placebo, with no safety concerns observed.
eurekalert.org
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Trial assesses antibody therapy for chronic a

Clazakizumab, targeting IL-6, failed to meet primary efficacy outcomes in the IMAGINE Phase 3 trial for chronic active antibody-mediated rejection in kidney transplant recipients, according to a final analysis. No significant difference in kidney function was observed between clazakizumab and placebo, with no safety concerns reported.
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