Quizartinib
- Generic Name
- Quizartinib
- Brand Names
- Vanflyta
- Drug Type
- Small Molecule
- Chemical Formula
- C29H32N6O4S
- CAS Number
- 950769-58-1
- Unique Ingredient Identifier
- 7LA4O6Q0D3
- Background
Quizartinib is an oral and potent fms-like tyrosine kinase 3 (FLT3) inhibitor and it is the first drug developed specifically targeting FLT3, as other agents with FLT3 inhibition activities were investigated with other targets in mind. Additionally, quizartinib also demonstrates inhibitory activity toward FLT3 with internal tandem duplication (ITD), although...
- Indication
Quizartinib is indicated in combination with standard cytarabine and anthracycline induction and cytarabine consolidation, and as maintenance monotherapy following consolidation chemotherapy, for the treatment of adult patients with newly diagnosed acute myeloid leukemia (AML) that is FLT3 internal tandem duplication (ITD)-positive as detected by an FDA-appr...
- Associated Conditions
- Newly Diagnosed Acute Myeloid Leukemia (AML)
- Associated Therapies
- -
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