Von Willebrand factor human
- Generic Name
- Von Willebrand factor human
- Brand Names
- Vonvendi, Wilate
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 109319-16-6
- Unique Ingredient Identifier
- ZE22NE22F1
- Background
The human von Willebrand factor (vWF) is a human plasma-derived vWF, an endogenous large multimeric plasma glycoprotein involved in hemostasis. It serves a dual role in hemostasis by mediating platelet adhesion and aggregation at the site of blood vessel injury and stabilizing procoagulant factor VIII (FVIII). Exogenous sources of vWF are used to restore fun...
- Indication
The von Willebrand factor (vWF) is indicated to manage and control bleeding episodes in adults with von Willebrand disease. It is also used for perioperative management of bleeding in these patients. It is also used for routine prophylaxis to reduce the frequency of bleeding episodes in patients with severe Type 3 von Willebrand disease receiving on-demand t...
- Associated Conditions
- Bleeding, Perioperative Blood Loss
- Associated Therapies
- Perioperative bleeding management therapy
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