Mifamurtide
- Generic Name
- Mifamurtide
- Brand Names
- Mepact
- Drug Type
- Small Molecule
- Chemical Formula
- C59H110N6NaO20P
- CAS Number
- 83461-56-7
- Unique Ingredient Identifier
- 1LM890Q4FY
- Background
Mifamurtide is an immunomodulator with antitumor activity via activation of macrophages and monocytes. Also called L-MTP-PE, mifamurtide may be a liposomal form of of the active ingredient MTP-PE, which is a synthetic, less pyrogenic, and longer-acting derivative of muramyl dipeptide (MDP). MDP is a motif present in all gram-positive and gram-negative bacter...
- Indication
Indicated in children, adolescents and young adults for the treatment of high-grade, resectable, non-metastatic osteosarcoma after macroscopically complete surgical resection, typically in combination with post-operative multi-agent chemotherapy .
- Associated Conditions
- High-grade, nonmetastatic Osteosarcoma, Resectable, nonmetastatic Osteosarcoma
- Associated Therapies
- -
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