Overview
Dexchlorpheniramine is a potent S-enantiomer of chlorpheniramine. The salt form dexchlorpheniramine maleate as the active ingredient is available as a prescription drug indicated for adjunctive therapy for allergic and anaphylactic reactions. It is an antihistamine drug with anticholinergic (drying) and sedative actions. It disrupts histamine signaling by competing with histamine for cell receptor sites on effector cells.
Background
Dexchlorpheniramine is a potent S-enantiomer of chlorpheniramine. The salt form dexchlorpheniramine maleate as the active ingredient is available as a prescription drug indicated for adjunctive therapy for allergic and anaphylactic reactions. It is an antihistamine drug with anticholinergic (drying) and sedative actions. It disrupts histamine signaling by competing with histamine for cell receptor sites on effector cells.
Indication
No indication information available.
Associated Conditions
- Allergy to Tree Pollen
- Common Cold
- Conjunctivitis
- Dermatitis
- Insect Bites
- Pruritus
- Rhinitis
- Sunburn
- Urticaria
- Vasomotor Rhinitis
Clinical Trials
Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2021/01/08 | Phase 3 | Recruiting | |||
2017/12/11 | Phase 3 | Active, not recruiting | Genzyme, a Sanofi Company | ||
2016/02/05 | Phase 3 | Completed | University Hospital, Bordeaux | ||
2015/10/22 | Phase 1 | Completed | Genzyme, a Sanofi Company | ||
2015/05/12 | Phase 4 | Completed | |||
2012/11/02 | Phase 3 | UNKNOWN | EMS | ||
2012/02/08 | Phase 3 | Completed | EMS | ||
2012/02/08 | Phase 3 | Terminated | EMS | ||
2010/11/10 | Phase 3 | UNKNOWN | Mantecorp Industria Quimica e Farmaceutica Ltd. | ||
2010/11/03 | Phase 3 | UNKNOWN | Mantecorp Industria Quimica e Farmaceutica Ltd. |
FDA Drug Approvals
Approved Product | Manufacturer | NDC Code | Route | Strength | Effective Date |
|---|---|---|---|---|---|
| No FDA approvals found for this drug. | |||||
EMA Drug Approvals
Approved Product | Authorization Holder | Status | Issued Date |
|---|---|---|---|
| No EMA approvals found for this drug. | |||
HSA Drug Approvals
Approved Product | Manufacturer | Approval Number | Dosage Form | Strength | Approval Date |
|---|---|---|---|---|---|
| No HSA approvals found for this drug. | |||||
NMPA Drug Approvals
Approved Product | Company | Approval Number | Drug Type | Dosage Form | Approval Date |
|---|---|---|---|---|---|
| No NMPA approvals found for this drug. | |||||
PPB Drug Approvals
Approved Product | Registration No. | Company | Licence No. | Strength | Registration Date |
|---|---|---|---|---|---|
| No PPB approvals found for this drug. | |||||
TGA Drug Approvals
Approved Product | ARTG ID | Sponsor | Registration Type | Status | Registration Date |
|---|---|---|---|---|---|
| No TGA approvals found for this drug. | |||||