CPI-1205

Generic Name
CPI-1205
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C27H33F3N4O3
CAS Number
1621862-70-1
Unique Ingredient Identifier
455J2479FY
Background

Potent and selective histone methyltransferase EZH2 inhibitor.

Associated Conditions
-
Associated Therapies
-

ORIOn-E: A Study Evaluating CPI-1205 in Patients With Advanced Solid Tumors

Phase 1
Completed
Conditions
Interventions
First Posted Date
2018-05-16
Last Posted Date
2022-05-18
Lead Sponsor
Constellation Pharmaceuticals
Target Recruit Count
24
Registration Number
NCT03525795
Locations
๐Ÿ‡บ๐Ÿ‡ธ

START Midwest, Grand Rapids, Michigan, United States

๐Ÿ‡บ๐Ÿ‡ธ

South Texas Oncology & Hematology, San Antonio, Texas, United States

๐Ÿ‡บ๐Ÿ‡ธ

The University of Texas - MD Anderson Cancer Center, Houston, Texas, United States

ProSTAR: A Study Evaluating CPI-1205 in Patients With Metastatic Castration Resistant Prostate Cancer

First Posted Date
2018-03-29
Last Posted Date
2021-07-26
Lead Sponsor
Constellation Pharmaceuticals
Target Recruit Count
242
Registration Number
NCT03480646
Locations
๐Ÿ‡บ๐Ÿ‡ธ

University of Illinois Hospital and Health Systems, Chicago, Illinois, United States

๐Ÿ‡บ๐Ÿ‡ธ

John Hopkins Kimmel Cancer Center, Baltimore, Maryland, United States

๐Ÿ‡บ๐Ÿ‡ธ

Dana Farber Cancer Institute, Boston, Massachusetts, United States

and more 38 locations

A Study Evaluating CPI-1205 in Patients With B-Cell Lymphomas

Phase 1
Completed
Conditions
Interventions
First Posted Date
2015-03-23
Last Posted Date
2022-05-18
Lead Sponsor
Constellation Pharmaceuticals
Target Recruit Count
41
Registration Number
NCT02395601
Locations
๐Ÿ‡บ๐Ÿ‡ธ

John Theurer Cancer Center, Hackensack, New Jersey, United States

๐Ÿ‡บ๐Ÿ‡ธ

Massachusetts General Hospital, Boston, Massachusetts, United States

๐Ÿ‡บ๐Ÿ‡ธ

Sarah Cannon Research Institute, Nashville, Tennessee, United States

and more 3 locations
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