Calaspargase pegol
- Generic Name
- Calaspargase pegol
- Brand Names
- Asparlas
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 941577-06-6
- Unique Ingredient Identifier
- T9FVH03HMZ
- Background
Asparaginase is an important agent used to treat acute lymphoblastic leukemia (ALL) . Asparagine is incorporated into most proteins, and the synthesis of proteins is stopped when asparagine is absent, which inhibits RNA and DNA synthesis, resulting in a halt in cellular proliferation. This forms the basis of asparaginase treatment in ALL , , .
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- Indication
This drug is is an asparagine specific enzyme indicated as a component of a multi-agent chemotherapeutic regimen for the treatment of acute lymphoblastic leukemia in pediatric and young adult patients age 1 month to 21 years .
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- Associated Conditions
- Acute Lymphoblastic Leukemia (ALL)
- Associated Therapies
- -
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