Filgotinib

Generic Name
Filgotinib
Brand Names
Jyseleca
Drug Type
Small Molecule
Chemical Formula
C21H23N5O3S
CAS Number
1206161-97-8
Unique Ingredient Identifier
3XVL385Q0M
Background

Rheumatoid arthritis (RA) is a chronic, autoimmune, systemic, and inflammatory disease that causes synovial joint symptoms and can limit range of motion in severe cases. The disease is associated with extra-articular manifestations, progressive disability, and comorbidities including cardiovascular disease and mental disorders. 50-70% of patients with RA are...

Indication

Filgotinib is indicated for the treatment of active moderate to severe rheumatoid arthritis alone or in combination with methotrexate. Filgotinib is currently reserved for patients who are unable to tolerate or who have not responded adequately to one or more disease-modifying anti-rheumatic drugs (DMARDS).
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Associated Conditions
Active, Moderate to Severe Rheumatoid Arthritis, Moderately to Severely Active Ulcerative Colitis
Associated Therapies
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