Human interleukin-2

Generic Name
Human interleukin-2
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
-
Unique Ingredient Identifier
FNO32LO217
Background

Human interleukin-2 is under investigation in clinical trial NCT03475134 (TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in mMEL).

Associated Conditions
-
Associated Therapies
-

MG4101 Plus Rituximab Including Lymphodepletion in Patient With r/r NHL B-cell Origin

First Posted Date
2018-12-19
Last Posted Date
2020-07-28
Lead Sponsor
GC Cell Corporation
Target Recruit Count
9
Registration Number
NCT03778619
Locations
🇰🇷

Asan Medical Center, Seoul, Korea, Republic of

🇰🇷

Samsung Medical Center, Seoul, Korea, Republic of

🇰🇷

Seoul National Univ. Hospital, Seoul, Korea, Republic of

Dose-escalation, Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Patients with R/r NHL and R/r B-cell ALL

First Posted Date
2018-09-11
Last Posted Date
2024-12-16
Lead Sponsor
Imugene Limited
Target Recruit Count
129
Registration Number
NCT03666000
Locations
🇺🇸

Banner MD Anderson Cancer Center, Gilbert, Arizona, United States

🇺🇸

City of Hope, Duarte, California, United States

🇺🇸

H. Lee Moffitt Cancer Center, Tampa, Florida, United States

and more 18 locations

Pembrolizumab Plus Autologous Dendritic Cell Vaccine in Patients With PD-L1 Negative Advanced Mesothelioma Who Have Failed Prior Therapies

First Posted Date
2018-06-06
Last Posted Date
2024-10-01
Lead Sponsor
Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori
Target Recruit Count
18
Registration Number
NCT03546426
Locations
🇮🇹

Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST), Meldola, FC, Italy

High Dose IL 2 and Entinostat in RCC

Phase 2
Active, not recruiting
Conditions
Interventions
First Posted Date
2018-04-18
Last Posted Date
2023-09-01
Lead Sponsor
Roberto Pili
Target Recruit Count
46
Registration Number
NCT03501381
Locations
🇺🇸

Univeristy of Southern California, Los Angeles, California, United States

🇺🇸

Hematology Oncology Clinic, LLC, Baton Rouge, Louisiana, United States

🇺🇸

Nebraska Methodist Hospital, Omaha, Nebraska, United States

and more 2 locations

Anti-PD-1 Antibody With HD IL-2 in Metastatic Melanoma

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2018-03-23
Last Posted Date
2024-10-02
Lead Sponsor
Ralph Hauke
Target Recruit Count
1
Registration Number
NCT03476174
Locations
🇺🇸

Nebraska Cancer Specialists, Omaha, Nebraska, United States

TIL-ACT After NMA Chemo With IL-2 and Nivo Rescue in Metastatic Melanoma (mMEL)

First Posted Date
2018-03-23
Last Posted Date
2024-02-13
Lead Sponsor
Centre Hospitalier Universitaire Vaudois
Target Recruit Count
18
Registration Number
NCT03475134
Locations
🇨🇭

CHUV Oncology Department, Lausanne, Vaud, Switzerland

UCDCC#272: IL-2, Radiotherapy, and Pembrolizumab in Patients Refractory to Checkpoint Blockade

First Posted Date
2018-03-22
Last Posted Date
2023-04-10
Lead Sponsor
Megan Daly, MD
Target Recruit Count
45
Registration Number
NCT03474497
Locations
🇺🇸

UC Davis Medical Center, Sacramento, California, United States

🇺🇸

University of California Davis Medical Center, Sacramento, California, United States

Adoptive Cell Therapy Following a Reduced Intensity, Non-myeloablative, Lymphodepleting Induction Regimen in Metastatic Ovarian

First Posted Date
2018-01-26
Last Posted Date
2019-04-04
Lead Sponsor
Sheba Medical Center
Target Recruit Count
15
Registration Number
NCT03412526
Locations
🇮🇱

Sheba medical Center, Ramat Gan, Israel

TIL Therapy in Combination With Checkpoint Inhibitors for Metastatic Ovarian Cancer

First Posted Date
2017-09-19
Last Posted Date
2023-03-01
Lead Sponsor
Inge Marie Svane
Target Recruit Count
7
Registration Number
NCT03287674
Locations
🇩🇰

Center for Cancer Immune Therapy Dept. of Hematology/oncology, Copenhagen, Denmark

Novel Strategies to Improve Immunomodulation and Non-invasive Clinical Monitoring in VCA

First Posted Date
2017-08-07
Last Posted Date
2021-07-28
Lead Sponsor
Brigham and Women's Hospital
Target Recruit Count
2
Registration Number
NCT03241719
Locations
🇺🇸

Brigham and Women's Hospital, Boston, Massachusetts, United States

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