MedPath

Spartalizumab

Generic Name
Spartalizumab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
1935694-88-4
Unique Ingredient Identifier
QOG25L6Z8Z
Background

Spartalizumab is under investigation in clinical trial NCT02605967 (Safety and Efficacy Study of PDR001 in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma).

Associated Conditions
-
Associated Therapies
-

Combination of Capmatinib + Spartalizumab in Advanced Oesogastric Adenocarcinoma

Phase 2
Suspended
Conditions
Oesophageal Adenocarcinoma
Gastric Adenocarcinoma
First Posted Date
2021-11-26
Last Posted Date
2023-02-03
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
90
Registration Number
NCT05135845
Locations
🇫🇷

Centre François Leclerc, Dijon, France

🇫🇷

Centre Léon Bérard, Lyon, France

🇫🇷

Institut Universitaire du Cancer, Toulouse, France

and more 4 locations

DFF332 as a Single Agent and in Combination With Everolimus & Immuno-Oncology Agents in Advanced/Relapsed Renal Cancer & Other Malignancies

Phase 1
Active, not recruiting
Conditions
Carcinoma, Renal Cell
Interventions
Drug: DFF332
Drug: RAD001
Drug: PDR001
Drug: NIR178
First Posted Date
2021-05-20
Last Posted Date
2025-01-09
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
40
Registration Number
NCT04895748
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

WA Uni School Of Med, Saint Louis, Missouri, United States

🇺🇸

Memorial Sloane Ketterin Cancer Ctr, New York, New York, United States

and more 3 locations

Study of Safety and Efficacy of DKY709 Alone or in Combination With PDR001 in Patients With Advanced Solid Tumors.

Phase 1
Active, not recruiting
Conditions
Nasopharyngeal Carcinoma
Microsatellite Stable Colorectal Cancer
Carcinoma, Non-Small-Cell Lung
Melanoma
Triple Negative Breast Cancer
Interventions
Drug: DKY709
Drug: PDR001
First Posted Date
2019-03-27
Last Posted Date
2025-01-10
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
99
Registration Number
NCT03891953
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

🇺🇸

Sarah Cannon Research Institute, Nashville, Tennessee, United States

and more 1 locations

A Study of the Anti-PD1 Antibody PDR001, in Combination With Dabrafenib and Trametinib in Advanced Melanoma

Phase 3
Completed
Conditions
Melanoma
Interventions
First Posted Date
2016-11-18
Last Posted Date
2025-01-07
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
573
Registration Number
NCT02967692
Locations
🇺🇸

California Cancer Associates for Research and Excellence, Encinitas, California, United States

🇺🇸

UC Irvine Medical Center, Orange, California, United States

🇺🇸

Stanford Cancer Center, Stanford, California, United States

and more 15 locations
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