Flortaucipir F-18
- Generic Name
- Flortaucipir F-18
- Brand Names
- Tauvid
- Drug Type
- Small Molecule
- Chemical Formula
- C16H10FN3
- CAS Number
- 1522051-90-6
- Unique Ingredient Identifier
- T1JP1KYU9O
- Background
Flortaucipir F-18, also known as F-T807 and F-AV-1451, is a small indole molecule synthesized with a radioactive fluorine isotope. It is used as a marker in positron emission tomography (PET) imaging of patients suspected of having Alzheimer's disease. After crossing the blood-brain barrier, flortaucipir F-18 binds to aggregated tau protein, a hallmark of Al...
- Indication
Flortaucipir F-18 is a radioactive agent indicated for positron emission tomography (PET) imaging of aggregated tau neurofibrillary tangles (NFTs) in adult patients under evaluation for Alzheimer's disease. Flortaucipir F-18 is not indicated for use in patients under evaluation for chronic traumatic encephalopathy.
- Associated Conditions
- Alzheimer's Disease (AD)
- Associated Therapies
- -
Follow up 18F-AV-1451 Scan in Confirmatory Cohort Subjects From Study 18F-AV-1451-A05
- First Posted Date
- 2016-06-10
- Last Posted Date
- 2020-08-24
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 79
- Registration Number
- NCT02795780
- Locations
- 🇺🇸
Institute for Brain Aging and Dementia, UC Irvine, Irvine, California, United States
🇺🇸California Medical Clinic for Headache, Santa Monica, California, United States
🇺🇸University of Pennsylvania, Philadelphia, Pennsylvania, United States
18F-AV-1451 Autopsy Study
- First Posted Date
- 2015-08-05
- Last Posted Date
- 2020-09-07
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 156
- Registration Number
- NCT02516046
- Locations
- 🇺🇸
Cherlin Research, Los Gatos, California, United States
🇺🇸Syrentis Clinical Research, Santa Ana, California, United States
🇺🇸Neuropsychiatric Research Center of Southwest Florida, Fort Myers, Florida, United States
Augmenting Flortaucipir Dosimetry Estimates
- First Posted Date
- 2015-01-13
- Last Posted Date
- 2020-08-11
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 6
- Registration Number
- NCT02336360
- Locations
- 🇺🇸
Molecular NeuroImaging, New Haven, Connecticut, United States
Clinical Evaluation of Flortaucipir F 18
- Conditions
- Interventions
- First Posted Date
- 2014-10-30
- Last Posted Date
- 2020-09-10
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 179
- Registration Number
- NCT02278367
- Locations
- 🇺🇸
Yale University, New Haven, Connecticut, United States
🇺🇸Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, Nevada, United States
🇺🇸Banner Alzheimer's Institute, Phoenix, Arizona, United States
Tau Imaging in Professional Fighters
- Conditions
- Interventions
- First Posted Date
- 2014-10-30
- Last Posted Date
- 2020-09-10
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 35
- Registration Number
- NCT02278354
- Locations
- 🇺🇸
Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas, Nevada, United States
Tau Imaging in Subjects With Progressive Supranuclear Palsy, Corticobasal Degeneration and Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2014-06-19
- Last Posted Date
- 2020-08-28
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 29
- Registration Number
- NCT02167594
- Locations
- 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸UCSD Movement Disorder Clinic, La Jolla, California, United States
🇺🇸Molecular Neuroimaging, New Haven, Connecticut, United States
18F-AV-1451 and Florbetapir F 18 PET (Positron Emission Tomography) Imaging in Subjects at Risk for Chronic Traumatic Encephalopathy
- Conditions
- Interventions
- First Posted Date
- 2014-03-06
- Last Posted Date
- 2020-09-07
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 41
- Registration Number
- NCT02079766
- Locations
- 🇺🇸
Banner Alzheimer's Institute, Phoenix, Arizona, United States
🇺🇸Boston University, Boston, Massachusetts, United States
Imaging Characteristics of a Follow-up 18F-AV-1451 Scan
- Conditions
- Interventions
- First Posted Date
- 2014-01-31
- Last Posted Date
- 2020-09-07
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 44
- Registration Number
- NCT02051764
- Locations
- 🇺🇸
Hoag Memorial Hospital, Newport Beach, California, United States
🇺🇸UC Irvine Medical Center, Orange, California, United States
🇺🇸Massachusetts General Hospital, Boston, Massachusetts, United States
Analysis of 18F-AV-1451 PET Imaging in Cognitively Healthy, MCI, and AD Subjects
- Conditions
- Interventions
- First Posted Date
- 2013-12-20
- Last Posted Date
- 2020-09-22
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 383
- Registration Number
- NCT02016560
- Locations
- 🇺🇸
UC Irvine, Irvine, California, United States
🇺🇸Neurological Research Institute, Santa Monica, California, United States
🇺🇸University of Pennsylvania, Philadelphia, Pennsylvania, United States
A Study of Flortaucipir PET in Healthy Volunteers and Cognitively Impaired Subjects
- Conditions
- Interventions
- First Posted Date
- 2013-11-25
- Last Posted Date
- 2020-09-07
- Lead Sponsor
- Avid Radiopharmaceuticals
- Target Recruit Count
- 24
- Registration Number
- NCT01992380
- Locations
- 🇺🇸
Research Site, New Haven, Connecticut, United States
Drug Development Updates
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