Tezepelumab
- Generic Name
- Tezepelumab
- Brand Names
- Tezspire
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 1572943-04-4
- Unique Ingredient Identifier
- RJ1IW3B4QX
- Background
Asthma is a heterogeneous chronic obstructive respiratory disease with both "type 2" (T2) and T2-low endotypes characterized by reduced airflow, chronic inflammation, and airway remodelling. Thymic stromal lymphopoietin (TSLP), an innate pleiotropic IL-2-family cytokine, has emerged as a key upstream regulator of chronic inflammation across asthma endotypes....
- Indication
Tezepelumab is indicated as an add-on maintenance treatment for patients aged 12 years and older with severe asthma. In Europe, it is reserved for patients who are inadequately controlled despite maintenance treatment with high-dose inhaled corticosteroids plus another drug.
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- Associated Conditions
- Severe Asthma
- Associated Therapies
- -
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