Vopratelimab

Generic Name
Vopratelimab
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
2039148-04-2
Unique Ingredient Identifier
QXN20J93AH
Background

Vopratelimab is under investigation in clinical trial NCT02904226 (JTX-2011 Alone and in Combination With Anti-PD-1 or Anti-CTLA-4 in Subjects With Advanced and/or Refractory Solid Tumors).

Associated Conditions
-
Associated Therapies
-

Study of PD-1 Inhibitor JTX-4014 Alone and in Combination With Vopratelimab in Biomarker-selected Subjects With Metastatic NSCLC After One Prior Platinum-containing Regimen

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2020-09-16
Last Posted Date
2024-05-22
Lead Sponsor
Jounce Therapeutics, Inc.
Target Recruit Count
69
Registration Number
NCT04549025
Locations
🇺🇦

Kyiv Railway Clinical Hospital #3 of Branch Health Center of the PJSC Ukrainian Railway, Kyiv, Ukraine

🇬🇪

Arensia Tbilisi - PPDS, Tbilisi, Georgia

🇭🇺

Veszprem Megyei Tudogyogyintezet, Farkasgyepű, Hungary

and more 69 locations

Vopratelimab (JTX-2011) Alone and in Combination With Anti-Programmed Cell Death Protein 1 (PD-1) or Anti-Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) in Subjects With Advanced and/or Refractory Solid Tumors

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2020-03-24
Last Posted Date
2024-05-30
Lead Sponsor
Jounce Therapeutics, Inc.
Target Recruit Count
4
Registration Number
NCT04319224
Locations
🇺🇸

The University of Texas - MD Anderson Cancer Center, Houston, Texas, United States

🇺🇸

University of Virginia Health Systems, Charlottesville, Virginia, United States

🇺🇸

Washington University School of Medicine, Saint Louis, Missouri, United States

Vopratelimab and a CTLA-4 Inhibitor in PD-1/PD-L1 Inhibitor Experienced Subjects With NSCLC or Urothelial Cancer

Phase 2
Completed
Conditions
Interventions
First Posted Date
2019-06-18
Last Posted Date
2022-09-10
Lead Sponsor
Jounce Therapeutics, Inc.
Target Recruit Count
61
Registration Number
NCT03989362
Locations
🇺🇸

University of Southern California Medical Center, Los Angeles, California, United States

🇺🇸

University of Maryland - Marlene and Stewart Greenebaum Cancer Center, Baltimore, Maryland, United States

🇺🇸

Allegheny Health Network Research Institute, Pittsburgh, Pennsylvania, United States

and more 18 locations
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