Ciforadenant

Generic Name
Ciforadenant
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C20H21N7O3
CAS Number
1202402-40-1
Unique Ingredient Identifier
8KFO2187CP
Background

Ciforadenant is under investigation in clinical trial NCT02253745 (Safety, Tolerability, PK & Efficacy of V81444 in Volunteers With Attention Deficit/ Hyperactivity Disorder (ADHD)).

Associated Conditions
-
Associated Therapies
-
globenewswire.com
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Adenosine Antagonists Clinical Trial Pipeline Analysis: 10+

Adenosine antagonists market growth driven by R&D in neurodegenerative diseases, oncology, and cardiovascular disorders. Innovations in formulation and delivery systems enhance efficacy and safety, increasing adoption. Key companies include Arcus Biosciences, Corvus Pharmaceuticals, Portage Biotech, Palobiofarm, iTeos Therapeutics. Promising drugs like Etrumadenant, Ciforadenant, PORT-6, and Inupadenant are in various clinical trial phases.
biospace.com
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Corvus Pharmaceuticals Announces New Data Highlighting Potential of Ciforadenant

New data presented at SITC 39th Annual Meeting highlights ciforadenant's potential to overcome anti-PD1 resistance in mCRPC, identifying SPP1+ myeloid cells and adenosine signaling as key mechanisms.
firstwordpharma.com
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Corvus Pharmaceuticals Announces New Data Highlighting Potential of Ciforadenant to ...

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globenewswire.com
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Corvus Pharmaceuticals Announces New Data Highlighting

Corvus Pharmaceuticals presents data on ciforadenant's potential to overcome anti-PD1 resistance in mCRPC, identifying SPP1+ myeloid cells and adenosine signaling as key mechanisms. The study, led by Dr. Lawrence Fong, showed ciforadenant's efficacy in reducing immunosuppression and enhancing anti-PD1 therapy sensitivity in a murine model, consistent with clinical trial data.
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