Soticlestat
- Generic Name
- Soticlestat
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C23H23N3O2
- CAS Number
- 1429505-03-2
- Unique Ingredient Identifier
- 1766MU795L
- Associated Conditions
- -
- Associated Therapies
- -
Novel Drug Fails for Two Rare Seizure Disorders
Soticlestat failed in phase III trials for Dravet and Lennox-Gastaut syndromes, missing primary endpoints. While it showed significant reduction in convulsive seizures for Dravet patients with SCN1A mutation, overall results were neutral. Takeda's future for the drug looks dim as FDA does not see substantial evidence of effectiveness.
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