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Tegavivint

Generic Name
Tegavivint
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C28H36N4O6S2
CAS Number
1227637-23-1
Unique Ingredient Identifier
18AP231HUP
Associated Conditions
-
Associated Therapies
-

Tegavivint for Treating Patients with Relapsed or Refractory Large B-Cell Lymphoma

Phase 1
Recruiting
Conditions
Recurrent Diffuse Large B-Cell Lymphoma Activated B-Cell Type
Recurrent Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type
Recurrent High Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements
Recurrent High Grade B-Cell Lymphoma with MYC, BCL2, and BCL6 Rearrangements
Refractory Diffuse Large B-Cell Lymphoma Activated B-Cell Type
Refractory Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type
Refractory High Grade B-Cell Lymphoma with MYC and BCL2 or BCL6 Rearrangements
Refractory High Grade B-Cell Lymphoma with MYC, BCL2, and BCL6 Rearrangements
Transformed Indolent B-Cell Non-Hodgkin Lymphoma to Diffuse Large B-Cell Lymphoma
Interventions
Procedure: Biospecimen Collection
Procedure: Computed Tomography
Procedure: Positron Emission Tomography
Drug: Tegavivint
First Posted Date
2023-03-06
Last Posted Date
2025-01-06
Lead Sponsor
Lapo Alinari
Target Recruit Count
20
Registration Number
NCT05755087
Locations
🇺🇸

Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States

Osimertinib and Tegavivint As First-Line Therapy for the Treatment of Metastatic EGFR-Mutant Non-small Cell Lung Cancer

Phase 1
Recruiting
Conditions
Metastatic Lung Non-Small Cell Carcinoma
Stage IV Lung Cancer AJCC V8
Stage IVA Lung Cancer AJCC V8
Stage IVB Lung Cancer AJCC V8
Interventions
First Posted Date
2021-03-03
Last Posted Date
2025-01-01
Lead Sponsor
Ohio State University Comprehensive Cancer Center
Target Recruit Count
24
Registration Number
NCT04780568
Locations
🇺🇸

Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States

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