Tusamitamab ravtansine

Generic Name
Tusamitamab ravtansine
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
2254086-60-5
Unique Ingredient Identifier
DSS3BE2ZXN
Background

Tusamitamab ravtansine is an antibody-drug conjugate that targets carcinoembryonic antigen-related cell adhesion molecule-5 (CEACAM5).

Associated Conditions
-
Associated Therapies
-

INTRUSION: Unraveling the INTRatUmoral PK/PD relatION for SAR408701

First Posted Date
2023-01-30
Last Posted Date
2024-02-28
Lead Sponsor
Erasmus Medical Center
Registration Number
NCT05703555
Locations
🇳🇱

Erasmus MC, Rotterdam, Netherlands

Effect of Tusamitamab Ravtansine on QTc Interval in Participants With Metastatic Solid Tumors

Phase 1
Terminated
Conditions
Interventions
First Posted Date
2022-06-23
Last Posted Date
2024-06-07
Lead Sponsor
Sanofi
Target Recruit Count
56
Registration Number
NCT05429762
Locations
🇺🇸

Mary Crowley Cancer Research Center Site Number : 8400002, Dallas, Texas, United States

🇪🇸

Investigational Site Number : 7240002, Barcelona, Catalunya [Cataluña], Spain

🇹🇷

Investigational Site Number : 7920001, Ankara, Turkey

and more 4 locations

Tusamitamab Ravtansine in NSQ NSCLC Participants With Negative or Moderate CEACAM5 Expression Tumors and High Circulating CEA

First Posted Date
2022-02-17
Last Posted Date
2024-12-13
Lead Sponsor
Sanofi
Target Recruit Count
22
Registration Number
NCT05245071
Locations
🇫🇷

Investigational Site Number : 2500001, Creteil, France

🇯🇵

Investigational Site Number : 3920003, Sunto Gun, Shizuoka, Japan

🇯🇵

Investigational Site Number : 3920005, Hirakata-shi, Osaka, Japan

and more 32 locations

Tusamitamab Ravtansine Monotherapy and in Combination in Patients With CEACAM5-positive Advanced Solid Tumors

First Posted Date
2020-12-09
Last Posted Date
2024-08-13
Lead Sponsor
Sanofi
Target Recruit Count
50
Registration Number
NCT04659603
Locations
🇹🇷

Investigational Site Number : 7920004, Ankara, Turkey

🇳🇱

Investigational Site Number : 5280001, Rotterdam, Netherlands

🇹🇷

Investigational Site Number : 7920003, Adana, Turkey

and more 26 locations
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