DaxibotulinumtoxinA

Generic Name
DaxibotulinumtoxinA
Brand Names
Botox, Botox Cosmetic, Daxxify, Dysport, Xeomin
Drug Type
Biotech
Chemical Formula
-
CAS Number
93384-43-1
Unique Ingredient Identifier
E211KPY694
Background

DaxibotulinumtoxinA is an acetylcholine release inhibitor and neuromuscular blocking agent. It is a botulinum toxin without accessory proteins purified from the bacterium Clostridium botulinum type A, the gram-positive anaerobic bacterium primarily present in soil. C. botulinum is known to produce toxins that can cause botulism in humans.
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Indication

DaxibotulinumtoxinA is indicated for the temporary improvement in the appearance of moderate to severe glabellar lines associated with corrugator and/or procerus muscle activity in adult patients. It is also used for the treatment of cervical dystonia in adult patients.

Associated Conditions
Cervical Dystonia, Moderate Glabellar Frown Lines (GL), Severe Glabellar Frown Lines (GL)
Associated Therapies
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pharmexec.com
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FDA Approves Allergan Aesthetics' Botox Cosmetic for Moderate to Severe Vertical Platysma Bands

FDA approves Allergan Aesthetics' Botox Cosmetic for treating moderate to severe vertical platysma bands, offering a nonsurgical option for neck band improvement. Phase III studies showed significant improvement and patient satisfaction. Potential adverse effects include excessive weakness and dysphagia.
healio.com
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FDA approves Botox Cosmetic for platysma bands

FDA approves Botox Cosmetic for platysma bands, marking the first neurotoxin for this use and expanding its aesthetic indications to four.
newbeauty.com
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Botox Receives FDA Approval for Treating Neck Bands

Botox Cosmetic receives FDA approval for treating moderate to severe vertical neck bands (platysmal bands), marking its first approval beyond facial areas. This new use allows for complete rejuvenation, including the neck, with doses of 26, 31, or 36 units depending on severity. Botox now has four FDA-approved aesthetic uses: forehead lines, frown lines, crow’s feet, and platysmal bands.
biospace.com
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New Phase III READY-4 Data Demonstrate Long-Term Safety and Efficacy of ...

Galderma announces phase III READY-4 trial data showing long-term safety of RelabotulinumtoxinA for frown lines and crow’s feet, with efficacy and patient satisfaction maintained across multiple treatments. The study met primary and secondary endpoints, with mild or moderate treatment-emergent adverse events reported by 18% of participants. RelabotulinumtoxinA, developed using PEARL™ Technology, is the first ready-to-use liquid neuromodulator optimized for simple volumetric dosing.
pharmabiz.com
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US FDA approves Allergan's Botox Cosmetic for moderate to severe vertical bands

Allergan Aesthetics, an AbbVie company, announced US FDA approval of Botox Cosmetic for temporary improvement in moderate to severe vertical bands connecting the jaw and neck. This marks the fourth aesthetic indication for Botox Cosmetic, expanding its use beyond facial lines. Clinical studies showed significant improvement in platysma band appearance, with 65% and 62% of patients reporting satisfaction 14 days post-treatment.
seekingalpha.com
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AbbVie Botox use expands beyond face (ABBV:NYSE)

FDA approves fourth indication for AbbVie's Botox Cosmetic, expanding its use beyond facial wrinkles.
tipranks.com
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Allergan's BOTOX Cosmetic gets FDA approval in jaw-neck bands

Allergan Aesthetics, an AbbVie company, announces U.S. FDA approval of BOTOX Cosmetic for temporary improvement in moderate to severe vertical platysma bands in adults, expanding its aesthetic indications beyond the face.
drugs.com
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Botox Cosmetic (onabotulinumtoxinA) Receives FDA Approval for Moderate to Severe Vertical Bands Connecting the Jaw and Neck (Platysma Bands)

Allergan Aesthetics announces FDA approval of Botox Cosmetic for temporary improvement in moderate to severe vertical bands connecting the jaw and neck (platysma bands) in adults, expanding its aesthetic indications beyond the face.

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