DaxibotulinumtoxinA
- Generic Name
- DaxibotulinumtoxinA
- Brand Names
- Botox, Botox Cosmetic, Daxxify, Dysport, Xeomin
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 93384-43-1
- Unique Ingredient Identifier
- E211KPY694
- Background
DaxibotulinumtoxinA is an acetylcholine release inhibitor and neuromuscular blocking agent. It is a botulinum toxin without accessory proteins purified from the bacterium Clostridium botulinum type A, the gram-positive anaerobic bacterium primarily present in soil. C. botulinum is known to produce toxins that can cause botulism in humans.
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- Indication
DaxibotulinumtoxinA is indicated for the temporary improvement in the appearance of moderate to severe glabellar lines associated with corrugator and/or procerus muscle activity in adult patients. It is also used for the treatment of cervical dystonia in adult patients.
- Associated Conditions
- Cervical Dystonia, Moderate Glabellar Frown Lines (GL), Severe Glabellar Frown Lines (GL)
- Associated Therapies
- -
Botulinum-A Toxin Injection for Detrusor Hyperreflexia in Spinal Cord Injury: A Non-Surgical Approach.
- Conditions
- First Posted Date
- 2005-12-06
- Last Posted Date
- 2015-06-26
- Lead Sponsor
- US Department of Veterans Affairs
- Registration Number
- NCT00262496
- Locations
- 🇺🇸
Miami VA Medical Center, Miami, Florida, United States
Botox as a Treatment for Interstitial Cystitis in Women
- Conditions
- Interventions
- First Posted Date
- 2005-09-19
- Last Posted Date
- 2012-10-12
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 20
- Registration Number
- NCT00194610
Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2021-01-22
- Target Recruit Count
- 33
- Registration Number
- NCT00178646
- Locations
- 🇺🇸
Memorial Hermann Hospital, Houston, Texas, United States
🇺🇸Kessler Institute for Rehabiliation, West Orange, New Jersey, United States
Comparative Trial of Botox in the Management of Children With Congenital Muscular Torticollis
- Conditions
- First Posted Date
- 2005-09-15
- Last Posted Date
- 2015-05-06
- Lead Sponsor
- University of British Columbia
- Registration Number
- NCT00175604
- Locations
- 🇨🇦
British Columbia Children's Hospital, Dept. of Orthopedics, Vancouver, British Columbia, Canada
Efficacy of Botox in Patients With Idiopathic Clubfoot
- Conditions
- First Posted Date
- 2005-09-09
- Last Posted Date
- 2022-05-18
- Lead Sponsor
- University of British Columbia
- Target Recruit Count
- 500
- Registration Number
- NCT00152334
- Locations
- 🇨🇦
BC Children's Hospital, Department of Orthopaedics, Vancouver, British Columbia, Canada
A Double-Blind, Randomized Control Trial Comparing Botulinum Toxin Type A (Botox) and Placebo in the Treatment of Idiopathic Clubfoot
- Conditions
- First Posted Date
- 2005-09-09
- Last Posted Date
- 2018-05-17
- Lead Sponsor
- University of British Columbia
- Target Recruit Count
- 36
- Registration Number
- NCT00152347
- Locations
- 🇨🇦
BC Children's Hospital, Department of Orthopaedics, Vancouver, British Columbia, Canada
Drug Development Updates
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