Lotilaner

Generic Name
Lotilaner
Brand Names
Xdemvy
Drug Type
Small Molecule
Chemical Formula
C20H14Cl3F6N3O3S
CAS Number
1369852-71-0
Unique Ingredient Identifier
HEH4938D7K
Background

Lotilaner is an ectoparasiticide that is a member of the isoxazoline family of compounds. Lotilaner has largely been used for veterinary uses as an antiparasitic agent to treat flea and tick infestations in animals. Lotilaner consists of two enantiomers: the S-enantiomer is active in vivo, while the R-enantiomer is reported to exhibit low biological activity...

Indication

Lotilaner is indicated for the treatment of Demodex blepharitis.

Associated Conditions
Demodex Blepharitis
Associated Therapies
-

Trial to Evaluate the Efficacy and Safety of TP-03, LIBRA Study

Phase 3
Completed
Conditions
Interventions
First Posted Date
2022-11-29
Last Posted Date
2024-05-21
Lead Sponsor
LianBio LLC
Target Recruit Count
163
Registration Number
NCT05629390
Locations
🇨🇳

Beijing Tongren Hospital, Beijing, Beijing, China

🇨🇳

Union Hospital, Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei, China

🇨🇳

Renmin Hospital of Wuhan University, Wuhan, Hubei, China

and more 18 locations
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