Buloxibutid

Generic Name
Buloxibutid
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C23H29N3O4S2
CAS Number
477775-14-7
Unique Ingredient Identifier
RC2V4W0EYC
Associated Conditions
-
Associated Therapies
-
labiotech.eu
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Idiopathic pulmonary fibrosis promising drugs: FOXO3 and beyond

Refoxy Pharma secures $9.58 million to develop IPF drug RP-01 targeting FOXO3. Boehringer Ingelheim plans NDA submission for nerandomilast. Insilico's ISM001-055 and Endeavor's ENV-101 show disease improvement. Vicore's buloxibutid and BMS' BMS-986278 also chart progress. Pliant's bexotegrast mitigates chronic cough in IPF. IPOs and partnerships fuel IPF therapeutic field.

Boehringer seeks approval for lung fibrosis drug following Phase III win

Boehringer Ingelheim seeks approval for nerandomilast after Phase III trial in idiopathic pulmonary fibrosis met primary endpoint. The trial, FIBRONEER-IPF, improved forced vital capacity after 52 weeks. Nerandomilast, a PDE4B inhibitor, received breakthrough therapy designation in 2022 and is also being tested in progressive fibrosing interstitial lung diseases.
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