ESK981

Generic Name: ESK981

Brand Names: -

Drug Type: Small Molecule

Chemical Formula: C_₃₅H_₃₅N_₇O_₄S

CAS Number: 856691-93-5

Unique Ingredient Identifier: J8AY0Z4CBP

Associated Conditions: -

Associated Therapies: -

Clinical Trials

Phase II trial of multi-tyrosine kinase inhibitor ESK981 in combination with PD-1

ESK981 + nivolumab showed no antitumor activity in AR+ mCRPC patients, with a maximum PSA decline of 14% and median rPFS of 3.7 months. The study was terminated due to futility.

Related Clinical Trials:

ESK981 and Nivolumab for the Treatment of Metastatic Castration Resistant Prostate Cancer

Drug Development Updates

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