MedPath

Faropenem

Generic Name
Faropenem
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C12H15NO5S
CAS Number
106560-14-9
Unique Ingredient Identifier
F52Y83BGH3
Background

Faropenem has been used in trials studying the treatment of Tuberculosis, Pulmonary Tuberculosis, and Community Acquired Pneumonia.

Indication

用于皮肤及软组织、呼吸系统、泌尿生殖系统及眼、耳、鼻、喉口腔等部位的敏感菌感染。

Associated Conditions
-
Associated Therapies
-

Whole Blood Bactericidal Activity (WBA) Against Mycobacterium Tuberculosis of Faropenem Plus Amoxicillin/Clavulanic Acid in Healthy Volunteers

Phase 1
Completed
Conditions
Tuberculosis
Interventions
Drug: Rifampicin
Drug: Faropenem
Drug: Amoxicillin/clavulanic acid 500mg/125mg
First Posted Date
2015-03-19
Last Posted Date
2017-04-05
Lead Sponsor
National University Hospital, Singapore
Target Recruit Count
43
Registration Number
NCT02393586
Locations
🇸🇬

National University Hospital, Singapore, Singapore

Trial of Faropenem and Cefadroxil (in Combination With Amoxicillin/Clavulanic Acid and Standard TB Drugs) in Patients With Pulmonary Tuberculosis: Measurement of Early Bactericidal Activity and Effects on Novel Biomarkers

Phase 2
Completed
Conditions
Pulmonary Tuberculosis
Interventions
Drug: Faropenem
Drug: Rifampicin
Drug: Amoxicillin/clavulanic acid
Drug: Cefadroxil
First Posted Date
2015-03-06
Last Posted Date
2020-03-23
Lead Sponsor
National University Hospital, Singapore
Target Recruit Count
58
Registration Number
NCT02381470
Locations
🇵🇭

Tropical Disease Foundation, Makati City, Philippines

🇵🇭

De La Salle Health Institute, Cavite, Philippines

🇸🇬

National University Hospital, Singapore, Singapore, Singapore

and more 3 locations

Phase 2 Trial to Evaluate the Early Bactericidal Activity, Safety and Tolerability of Meropenem Plus Amoxycillin/CA and Faropenem Plus Amoxycillin/CA in Adult Patients With Newly Diagnosed Pulmonary Tuberculosis

Phase 2
Completed
Conditions
Pulmonary Tuberculosis
Interventions
Drug: Rifafour e275
Drug: Meropenem
Drug: Faropenem
Drug: Amoxycillin/clavulanic acid
First Posted Date
2015-01-29
Last Posted Date
2018-09-13
Lead Sponsor
TASK Applied Science
Target Recruit Count
46
Registration Number
NCT02349841
Locations
🇿🇦

TASK Foundation NPC, Cape Town, Western Cape, South Africa

A Phase III Study of Faropenem in the Treatment of Adult Community-acquired Bacterial Pneumonia

Phase 3
Conditions
Community Acquired Pneumonia
Interventions
First Posted Date
2013-09-10
Last Posted Date
2013-09-10
Lead Sponsor
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Target Recruit Count
540
Registration Number
NCT01937832
Locations
🇨🇳

The Second Hospital of Jilin University, Changchun, Jilin, China

🇨🇳

The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

🇨🇳

Anhui Provincial Hospital, Hefei, Anhui, China

and more 4 locations
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