Hydromorphone
- Generic Name
- Hydromorphone
- Brand Names
- Dilaudid, Exalgo, Hydromorph Contin, Hydromorphone Hp Forte
- Drug Type
- Small Molecule
- Chemical Formula
- C17H19NO3
- CAS Number
- 466-99-9
- Unique Ingredient Identifier
- Q812464R06
- Background
Hydromorphone is a pure opioid, a semi-synthetic hydrogenated ketone derivative of morphine that has been available clinically since 1920. Structurally, hydromorphone derived from morphine in the modification of the hydroxyl group in the carbon 6 to a carbonyl and the absence of a double bond between the carbon 7 and 8. Due to these modifications, it present...
- Indication
Hydromorphone is indicated for the management of moderate to severe acute pain and severe chronic pain. Due to its addictive potential and overdose risk, hydromorphone is only prescribed when other first-line treatments have failed.
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- Associated Conditions
- Neuropathic Pain, Refractory Chronic Cough, Moderate to severe pain
- Associated Therapies
- -
Intrathecal Opioids for Colorectal Resection
- Conditions
- Interventions
- First Posted Date
- 2021-02-12
- Last Posted Date
- 2024-03-26
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 80
- Registration Number
- NCT04752033
- Locations
- 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States
The Effect of Esketamine on Patients Undergoing Tumor Surgery
- Conditions
- Interventions
- First Posted Date
- 2020-11-03
- Last Posted Date
- 2020-11-03
- Target Recruit Count
- 282
- Registration Number
- NCT04613869
- Locations
- 🇨🇳
The Second Affiliated Hospital of Zhejiang University anesthesiology department, Hangzhou, Zhejiang, China
Hydromorphone for ICU-analgesia in Patients With Non-mechanical Ventilation
- Conditions
- Interventions
- First Posted Date
- 2020-06-17
- Last Posted Date
- 2022-01-20
- Lead Sponsor
- Nanfang Hospital, Southern Medical University
- Target Recruit Count
- 530
- Registration Number
- NCT04436224
- Locations
- 🇨🇳
Southern medical university Nanfang hospital, Guangzhou, China
Multimodal Pain Management After Robotic-Assisted Total Laparoscopic Hysterectomy
- First Posted Date
- 2020-06-11
- Last Posted Date
- 2023-08-01
- Lead Sponsor
- State University of New York at Buffalo
- Target Recruit Count
- 68
- Registration Number
- NCT04429022
- Locations
- 🇺🇸
Millard Fillmore Suburban Hospital, Williamsville, New York, United States
Non-analgesic Effects Produced by Equipotent Analgesic Doses of Sufentanil, Hydromorphone, and Oxycodone
- Conditions
- Interventions
- First Posted Date
- 2020-05-20
- Last Posted Date
- 2024-05-30
- Lead Sponsor
- Peking University People's Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT04396587
- Locations
- 🇨🇳
Peking University People's Hospital, Beijing, Beijing, China
Effect of Opioid Infusion Rate on Abuse Liability Potential of Intravenous Hydromorphone for Cancer Pain
- Conditions
- Interventions
- First Posted Date
- 2020-03-05
- Last Posted Date
- 2024-10-28
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 84
- Registration Number
- NCT04296305
- Locations
- 🇺🇸
M D Anderson Cancer Center, Houston, Texas, United States
Liposomal Bupivacaine With or Without Hydromorphone for the Improvement of Pain Control After Laparotomy in Patients With Gynecological Malignancies
- Conditions
- Interventions
- First Posted Date
- 2020-02-06
- Last Posted Date
- 2024-10-16
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 105
- Registration Number
- NCT04258631
- Locations
- 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States
Comparing Rapid Micro-Induction and Standard Induction of Buprenorphine/Naloxone for Treatment of Opioid Use Disorder
- Conditions
- Interventions
- First Posted Date
- 2020-01-21
- Last Posted Date
- 2024-06-11
- Lead Sponsor
- University of British Columbia
- Target Recruit Count
- 50
- Registration Number
- NCT04234191
- Locations
- 🇨🇦
Vancouver General Hospital, Vancouver, British Columbia, Canada
Hydromorphone vs Fentanyl in Children Undergoing Tonsillectomy Surgery
- Conditions
- Interventions
- First Posted Date
- 2020-01-18
- Last Posted Date
- 2024-12-18
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 189
- Registration Number
- NCT04230681
- Locations
- 🇺🇸
Washington University School of Medicine/Barnes-Jewish Hospital, Saint Louis, Missouri, United States
ICE T for Post GYN Surgery Pain
- Conditions
- Interventions
- First Posted Date
- 2019-06-14
- Last Posted Date
- 2022-05-02
- Lead Sponsor
- MetroHealth Medical Center
- Target Recruit Count
- 66
- Registration Number
- NCT03987022
- Locations
- 🇺🇸
MetroHealth Medical Center, Cleveland, Ohio, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.