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Tiotropium

Generic Name
Tiotropium
Brand Names
Inspiolto Respimat, Spiriva, Spiriva Respimat, Stiolto
Drug Type
Small Molecule
Chemical Formula
C19H22NO4S2
CAS Number
186691-13-4
Unique Ingredient Identifier
0EB439235F

Overview

Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma. Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation. Tiotropium is more specific for the subset of muscarinic receptors commonly found in the lungs than ipratropium. Tiotropium was granted FDA approval on 30 January 2004.

Background

Tiotropium is a long-acting, antimuscarinic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD) and asthma. Tiotropium acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation and bronchodilation. Tiotropium is more specific for the subset of muscarinic receptors commonly found in the lungs than ipratropium. Tiotropium was granted FDA approval on 30 January 2004.

Indication

Tiotropium powder for inhalation is indicated for the maintenance of bronchospasm in COPD and to prevent exacerbations of COPD. A combination tiotropium and olodaterol metered inhalation spray is indicated for maintenance of COPD. A tiotropium inhalation spray is indicated for the maintenance of bronchospasm in COPD, to prevent exacerbations of COPD, and to treat asthma in patients 12 or more years old. A tiotropium metered inhalation spray is indicated for the maintenance of bronchospasm in COPD, to prevent exacerbations of COPD, and to treat asthma in patients 6 or more years old.

Associated Conditions

  • Asthma
  • Bronchitis
  • Bronchoconstriction
  • Chronic Bronchitis
  • Chronic Obstructive Pulmonary Disease (COPD)
  • Emphysema
  • Exacerbation of COPD

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

No Singapore products found for this drug

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