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Guanidine

Generic Name
Guanidine
Drug Type
Small Molecule
Chemical Formula
CH5N3
CAS Number
113-00-8
Unique Ingredient Identifier
JU58VJ6Y3B

Overview

A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.

Background

A strong organic base existing primarily as guanidium ions at physiological pH. It is found in the urine as a normal product of protein metabolism. It is also used in laboratory research as a protein denaturant. (From Martindale, the Extra Pharmacopoeia, 30th ed and Merck Index, 12th ed) It is also used in the treatment of myasthenia and as a fluorescent probe in HPLC.

Indication

For the reduction of the symptoms of muscle weakness and easy fatigability associated with the myasthenic syndrome of Eaton-Lambert. It is not indicated for treating myasthenia gravis.

Associated Conditions

  • Fatigue
  • Muscle Weakness

Clinical Trials

Phase 1
Recruiting
Posted: 2021/03/05
Sponsor:
Guangdong Provincial...
Early Phase 1
Posted: 2020/06/04
Sponsor:
Guangdong Provincial...

FDA Approved Products

No FDA products found for this drug

Singapore Approved Products

No Singapore products found for this drug

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