Icotinib

Generic Name
Icotinib
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C22H21N3O4
CAS Number
610798-31-7
Unique Ingredient Identifier
9G6U5L461Q
Background

Icotinib is a potent and specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)
...

Indication

Icotinib hydrochloride is a novel epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitor, exhibits encouraging efficacy and tolerability in patients with advanced non-small-cell lung cancer (NSCLC) who failed previous chemotherapy.

Associated Conditions
-
Associated Therapies
-

Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors

First Posted Date
2016-10-14
Last Posted Date
2021-09-09
Lead Sponsor
Li Peng
Target Recruit Count
10
Registration Number
NCT02934256
Locations
🇨🇳

Beijing Tiantan Hospital Affiliated to Capital Medical University, Beijing, China

The Role of Icotinib in the Perioperative Treatment of IIIA - IIIB NSCLC Patients With EGFR Mutation

First Posted Date
2016-06-30
Last Posted Date
2016-06-30
Lead Sponsor
Beijing Haidian Hospital
Target Recruit Count
67
Registration Number
NCT02820116
Locations
🇨🇳

Beijing Haidian Hospital, Beijing, Beijing, China

Conmana Combined With Thalidomide to Treat NSCLC

Phase 4
Conditions
Interventions
First Posted Date
2016-05-20
Last Posted Date
2016-05-20
Lead Sponsor
Henan Provincial People's Hospital
Target Recruit Count
67
Registration Number
NCT02778893
Locations
🇨🇳

XZhang, Zhengzhou, Henan, China

Cryotherapy Combine Icotinib for Advanced NSCLC Treatment

Phase 4
Completed
Conditions
Interventions
First Posted Date
2016-04-20
Last Posted Date
2020-05-27
Lead Sponsor
Fuda Cancer Hospital, Guangzhou
Target Recruit Count
60
Registration Number
NCT02744664

Alternating Icotinib and Chemotherapy for Advanced Non-small Cell Lung Cancer With EGFR Mutation

First Posted Date
2016-04-14
Last Posted Date
2020-07-01
Lead Sponsor
Henan Cancer Hospital
Target Recruit Count
60
Registration Number
NCT02737774
Locations
🇨🇳

Henan cancer hospital, Zhengzhou, Henan, China

High Dose Icotinib With Sequential SRS For NSCLC Patients Harboring EGFR Mutation With Brain Metastases

First Posted Date
2016-04-01
Last Posted Date
2019-02-19
Lead Sponsor
Betta Pharmaceuticals Co., Ltd.
Target Recruit Count
30
Registration Number
NCT02726568
Locations
🇨🇳

West China Hospital, Chengdu, Sichuan, China

Icotinib in Advanced Metastatic Patients With NSCLC Previously Treated With Chemotherapy

Phase 3
Completed
Conditions
Interventions
First Posted Date
2015-07-01
Last Posted Date
2015-07-01
Lead Sponsor
Betta Pharmaceuticals Co., Ltd.
Target Recruit Count
128
Registration Number
NCT02486354
Locations
🇨🇳

307 Hospital of PLA, Beijing, Beijing, China

🇨🇳

Jiangsu Cancer Hospital, Nanjing, Jiangsu, China

🇨🇳

Third Affiliated Hospital, Third Military Medical University, Chongqing, Chongqing, China

and more 7 locations

Icotinib as Adjuvant Therapy Compared With Standard Chemotherapy in Stage II-IIIA NSCLC With EGFR-mutation

First Posted Date
2015-05-19
Last Posted Date
2021-07-20
Lead Sponsor
Betta Pharmaceuticals Co., Ltd.
Target Recruit Count
320
Registration Number
NCT02448797
Locations
🇨🇳

307 Hospital of PLA, Beijing, Beijing, China

🇨🇳

Fujian Provincal Cancer Hospital, Fuzhou, Fujian, China

🇨🇳

The First Affiliated Hospital Of Guangzhou Medical Collage, Guangzhou, Guangdong, China

and more 5 locations

Chemotherapy of NSCLC With or Without Icotinib

Phase 2
Conditions
Interventions
First Posted Date
2015-04-30
Last Posted Date
2015-04-30
Lead Sponsor
Nanfang Hospital, Southern Medical University
Target Recruit Count
50
Registration Number
NCT02430974
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