Metformin

A stepped-wedge cluster-randomized clinical trial at 12 VA medical centers found the Virtual Breakthrough Series (VBTS) intervention did not reduce missed abnormal test results, though it may benefit low-performing sites.

High-intensity exercise reduces ghrelin levels and suppresses hunger more effectively, especially in females, according to a study in the Journal of the Endocrine Society.

Kamala Harris and Beyoncé rallied in Texas to encourage voter turnout, emphasizing reproductive rights and the impact of Supreme Court nominations on abortion access. Harris highlighted the 'horrific reality' of women denied medical care due to abortion bans, and the potential for Trump to appoint more justices if re-elected. Public polls show consistent support for abortion access, with 63% of Americans favoring it being legal in most or all cases.

Research on non-volatile memory and neuro-inspired computing has driven demand for integrating AI and pattern recognition into data processing, leading to attention on neuromorphic architectures due to their low power consumption and integrated storage/computing. Phase-change memory (PCM) with materials like GeTe is ideal for synaptic devices due to rapid transitions, high accuracy, and durability. GeTe, an alternative to GST, offers superior thermal stability and is promising for PCM and neuromorphic computing. Understanding temperature-dependent local structures and optical properties is crucial for further development of GeTe-based PCM devices.

Scientific foundations of health, diet, and immunity claims are often based on limited evidence; innovative approaches in nutrition immunology aim to close this credibility gap. Researchers explore short-term effects of specific dietary components and their molecular mechanisms on immunity. Modern diets may skew immune responses, but diet could also help treat health problems like cancers and chronic immune disorders. Studies on chitin, fasting, and high-fat diets reveal potential therapeutic targets for obesity and immune conditions. Human trials are challenging but crucial for confirming dietary impacts on immune systems.

MedTech develops medical devices for diagnosis and treatment, while BioTech uses biological processes to create drugs and therapies. Both fields are rapidly growing, driven by innovations and increasing demand for healthcare solutions, but face distinct regulatory challenges. Emerging technologies like AI and gene editing are set to revolutionize both fields, enhancing patient care and personalized medicine.

SHGM reveals FE domain dynamics in BTO during phase transitions, showing strong hysteresis and differing critical exponents for cubic-to-tetragonal and tetragonal-to-orthorhombic transitions.

With the election nearing, Kamala Harris and Donald Trump present contrasting views on pharma policies. Harris supports expanding Medicare's drug price negotiation power and cracking down on PBMs, attracting industry funding and Mark Cuban's support. Trump, initially advocating for lower drug prices, has shifted to align with industry lobbyists, opposing IRA provisions like Medicare's negotiation authority and the 'most-favored nations' policy.

ResisenseNet, a hybrid neural network with 1D-CNN, LSTM, and DNN modules, was trained to predict drug sensitivity in breast cancer. Ablation studies showed improved performance with module integration, achieving high accuracy and low loss. The model outperformed a baseline logistic classifier and demonstrated generalizability across different cancer types. SHAP analysis highlighted molecular descriptors' impact on drug behavior, guiding drug repurposing efforts for breast cancer treatment.