Phentermine

Generic Name
Phentermine
Brand Names
Adipex-P, Lomaira, Qsymia
Drug Type
Small Molecule
Chemical Formula
C10H15N
CAS Number
122-09-8
Unique Ingredient Identifier
C045TQL4WP
Background

Phentermine is a sympathomimetic amine anorectic agent and it was introduced in 1959 as part of an anti-obesity combination drug. It is chemically related to amphetamine and it is commonly referred to as an atypical amphetamine. Phentermine has not been reported an addictive potential which allows this agent to be classified under the Schedule IV drugs (low ...

Indication

Phentermine is indicated, alone or in combination with topiramate, as a short-term adjunct, not pass a few weeks, in a regimen of weight reduction based on exercise, behavioral modifications and caloric restriction in the management of exogenous obesity for patients with an initial body mass index (BMI) greater than 30 kg/m2 or greater than 27 kg/m2 in prese...

Associated Conditions
Obesity
Associated Therapies
Chronic Weight Management therapy

Studying the Effects of Phentermine on Eating Behavior

Phase 4
Completed
Conditions
Interventions
First Posted Date
2013-06-26
Last Posted Date
2017-07-31
Lead Sponsor
New York State Psychiatric Institute
Target Recruit Count
13
Registration Number
NCT01886937
Locations
🇺🇸

The New York State Psychiatric Institute at Columbia University Medical Center, New York, New York, United States

The Effect of Phentermine and B12 on Weight Loss Among Obese Patients

Early Phase 1
Completed
Conditions
Interventions
First Posted Date
2012-11-01
Last Posted Date
2015-08-13
Lead Sponsor
Dr. Michael Lang
Target Recruit Count
22
Registration Number
NCT01719185
Locations
🇺🇸

Brody Outpatient of Brody Medical Sciences Module D, Greenville, North Carolina, United States

Effect of Caloric Restriction on Fat Oxidation in Obese Men and Women (Magellan II)

First Posted Date
2012-06-11
Last Posted Date
2020-11-13
Lead Sponsor
AdventHealth Translational Research Institute
Target Recruit Count
39
Registration Number
NCT01616082
Locations
🇺🇸

Translational Research Institute for Metabolism and Diabetes, Orlando, Florida, United States

Study in Healthy Recreational Polydrug Users to Measure the Abuse Potential of TC-5214

First Posted Date
2011-12-26
Last Posted Date
2012-03-22
Lead Sponsor
AstraZeneca
Registration Number
NCT01500018

Phentermine/Gastric Band Weight Loss Study

Not Applicable
Withdrawn
Conditions
Interventions
First Posted Date
2008-10-13
Last Posted Date
2022-04-21
Lead Sponsor
Wake Forest University Health Sciences
Registration Number
NCT00771654

A Study Comparing Multiple Doses of VI-0521 With Placebo and Their Single-agent Constituents for Treatment of Obesity in Adults

Phase 3
Completed
Conditions
Interventions
First Posted Date
2007-11-26
Last Posted Date
2015-03-30
Lead Sponsor
VIVUS LLC
Target Recruit Count
756
Registration Number
NCT00563368
Locations
🇺🇸

Research Site, Philadelphia, Pennsylvania, United States

Pharmacokinetic Comparison of Multiple Formulations of Topiramate and Phentermine in Obese Adults

Phase 1
Completed
Conditions
Interventions
First Posted Date
2007-08-20
Last Posted Date
2011-06-08
Lead Sponsor
VIVUS LLC
Target Recruit Count
64
Registration Number
NCT00518466
Locations
🇺🇸

VIVUS, Inc., Mountain View, California, United States

A Study to Examine the Safety, Tolerability, and Body Weight Effect of Pramlintide Alone and in Combination With Oral Antiobesity Agents in Overweight and Obese Subjects

First Posted Date
2006-11-22
Last Posted Date
2015-03-06
Lead Sponsor
AstraZeneca
Target Recruit Count
258
Registration Number
NCT00402077
Locations
🇺🇸

Research Site, San Antonio, Texas, United States

Cardiovascular System in Obesity: Effect of Treatment

Phase 2
Completed
Conditions
First Posted Date
1999-10-28
Last Posted Date
2013-11-26
Lead Sponsor
National Heart, Lung, and Blood Institute (NHLBI)
Registration Number
NCT00000506
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