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Pemetrexed

Generic Name
Pemetrexed
Brand Names
Alimta, Ciambra, Pemfexy, Pemrydi Rtu, Pemetrexed Fresenius Kabi, Pemetrexed Baxter, Pemetrexed Krka, Pemetrexed medac, Pemetrexed Accord, Pemetrexed Sandoz, Armisarte (previously Pemetrexed Actavis)
Drug Type
Small Molecule
Chemical Formula
C20H21N5O6
CAS Number
137281-23-3
Unique Ingredient Identifier
04Q9AIZ7NO

Overview

Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative surgery. Its use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA in February 4, 2004.

Background

Pemetrexed is a chemotherapy drug that is manufactured and marketed by Eli Lilly and Company under the brand name Alimta. It is indicated for use in combination with cisplatin for the treatment of patients with malignant pleural mesothelioma whose disease is either unresectable or who are otherwise not candidates for curative surgery. Its use in non-small cell lung cancer has also been investigated. Pemetrexed was first approved by the FDA in February 4, 2004.

Indication

Pemetrexed is indicated for the treatment of the following conditions: Non-squamous non-small cell lung cancer (NSCLC) Malignant pleural mesothelioma

Associated Conditions

  • Metastatic Cervical Cancer
  • Metastatic Non-squamous Non Small Cell Lung Cancer
  • Metastatic Urothelial Carcinoma (UC)
  • Ovarian Cancer
  • Locally advanced nonsquamous non-small cell lung cancer
  • Recurrent, metastatic Non-squamous Non-small-cell Lung Cancer (NSQ NSCLC)
  • Unresectable Malignant Pleural Mesothelioma (MPM)
  • Unresectable Thymoma

FDA Approved Products

Pemetrexed
Manufacturer:Fresenius Kabi USA, LLC
Route:INTRAVENOUS
Strength:100 mg in 4 mL
Approved: 2022/01/12
NDC:63323-134
Pemetrexed
Manufacturer:Fresenius Kabi USA, LLC
Route:INTRAVENOUS
Strength:1 g in 40 mL
Approved: 2022/01/12
NDC:63323-622
Pemetrexed disodium
Manufacturer:Dr. Reddys Laboratories Inc
Route:INTRAVENOUS
Strength:100 mg in 4 mL
Approved: 2022/09/30
NDC:43598-386
Pemetrexed
Manufacturer:Meitheal Pharmaceuticals Inc.
Route:INTRAVENOUS
Strength:1 g in 40 mL
Approved: 2022/11/15
NDC:71288-148
Pemetrexed
Manufacturer:Waverley Pharma Inc
Route:INTRAVENOUS
Strength:100 mg in 4 mL
Approved: 2018/06/04
NDC:72338-100

Singapore Approved Products

No Singapore products found for this drug

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